Description

4-Amino-Piperidine-4-Carboxylic Acid Methyl Ester 2Hcl is a high-purity, protected piperidine derivative that serves as a critical chiral building block in advanced organic synthesis. This compound is essential for medicinal chemistry research and development, enabling the construction of complex molecular architectures. It is primarily utilized by pharmaceutical R&D teams and fine chemical manufacturers focused on creating novel active pharmaceutical ingredients (APIs) and other bioactive molecules.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of potential drug candidates targeting central nervous system (CNS) disorders, metabolic diseases, and infectious diseases.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization programs to explore new chemical entities.
• Peptidomimetic Synthesis: Serves as a constrained amino acid analog for designing and synthesizing peptide mimics with enhanced stability and bioavailability.
• Chemical Biology Probes: Employed in the development of tool compounds and molecular probes for studying biological pathways and target validation.
• Custom Synthesis & Contract Manufacturing: A valuable starting material for CDMOs (Contract Development and Manufacturing Organizations) producing bespoke compounds for client projects.
• Academic Research: Used in university and institutional laboratories for methodological development in asymmetric synthesis and heterocyclic chemistry.

Basic Information

Product Name	4-Amino-Piperidine-4-Carboxylic Acid Methyl Ester 2Hcl
CAS No.	161315-19-1
Molecular Formula	C8H18Cl2N2O2
Molecular Weight	245.15 g/mol
Synonyms	Methyl 4-Aminopiperidine-4-carboxylate dihydrochloride; 4-Amino-4-(methoxycarbonyl)piperidine dihydrochloride; 4-(Methoxycarbonyl)-4-aminopiperidine dihydrochloride; 4-Carbomethoxy-4-aminopiperidine dihydrochloride; 4-Aminoisonipecotic acid methyl ester dihydrochloride; 4-Aminopiperidine-4-carboxylic acid methyl ester hydrochloride (2:1); Piperidine-4-carboxylic acid, 4-amino-, methyl ester, dihydrochloride
EINECS	Contact for details

Quality Control

Our 4-Amino-Piperidine-4-Carboxylic Acid Methyl Ester 2Hcl is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and development applications. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.