Description

Rac trans-4-Cotininecarboxylic Acid is a high-purity chemical intermediate of significant interest in advanced organic synthesis. This compound is valued for its role as a key building block in the development of novel pharmaceutical agents and research chemicals. It is primarily utilized by R&D laboratories, pharmaceutical manufacturers, and fine chemical producers engaged in the synthesis of complex molecules for therapeutic and investigative purposes.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly in neuroscience and addiction research.
• Metabolite Standard: Used as a reference standard in analytical chemistry for the quantification and study of nicotine metabolites in biological samples.
• Biochemical Research: Serves as a tool compound for investigating nicotinic acetylcholine receptor pathways and related biochemical mechanisms.
• Fine Chemical Synthesis: Employed as a versatile building block for constructing complex molecular architectures in medicinal and process chemistry.
• Analytical Method Development: Utilized in the development and validation of chromatographic methods (HPLC, LC-MS) for metabolite detection.

Basic Information

Product Name	Rac trans-4-Cotininecarboxylic Acid
CAS No.	161171-06-8
Molecular Formula	C10H10N2O3
Molecular Weight	206.20 g/mol
Synonyms	trans-4-Cotininecarboxylic Acid (racemic); (±)-trans-4-Cotininecarboxylic Acid; 4-Carboxycotinine; 5-(3-Pyridinyl)-1-azabicyclo[2.2.2]octane-2-carboxylic Acid; Cotinine-4-carboxylic Acid; rac-trans-Cotinine-4-carboxylic Acid; 1-Methyl-5-(3-pyridinyl)-2-pyrrolidinecarboxylic Acid (trans, racemic); Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our Rac trans-4-Cotininecarboxylic Acid is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot is subjected to comprehensive analytical testing, including HPLC for assay and purity determination, and is supplied with a corresponding Certificate of Analysis (COA). We are committed to meeting the stringent requirements of research and pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.