Description

(4-Bromo-2-Chloro-6-Fluorophenyl)-1,1,2,3,3,3-Hexafluoropropyl Ether is a high-value, multi-halogenated aromatic ether building block designed for advanced chemical synthesis. This compound matters because its unique structure, featuring bromine, chlorine, and fluorine substituents, provides exceptional versatility for introducing specific steric and electronic properties into target molecules. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in fluorinated drug candidates targeting CNS disorders and oncology.
• Agrochemical Synthesis: Used in the research and production of next-generation herbicides, fungicides, and insecticides where the halogen pattern enhances biological activity and environmental stability.
• Liquid Crystal & OLED Material Precursor: Serves as a building block for fluorinated aromatic cores in advanced electronic materials, contributing to improved performance in displays and lighting.
• Polymer Modification: Employed to introduce halogenated phenyl ether groups into polymer chains, altering thermal stability, flame retardancy, and chemical resistance.
• Cross-Coupling Reactions: The bromo and chloro substituents make it an excellent substrate for selective palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig).
• Organic Synthesis Building Block: A versatile reagent for constructing complex polyhalogenated biaryl ethers and other architecturally challenging molecules in medicinal chemistry.

Basic Information

Product Name	(4-Bromo-2-Chloro-6-Fluorophenyl)-1,1,2,3,3,3-Hexafluoropropyl Ether
CAS No.	161045-78-9
Molecular Formula	C9H3BrClF7O
Molecular Weight	363.47 g/mol
Synonyms	1-(4-Bromo-2-chloro-6-fluorophenoxy)-1,1,2,3,3,3-hexafluoropropane; 4-Bromo-2-chloro-6-fluoro-1-(1,1,2,3,3,3-hexafluoropropoxy)benzene; 2-Chloro-4-bromo-6-fluoro-1-(1,1,2,3,3,3-hexafluoropropoxy)benzene; 1,1,2,3,3,3-Hexafluoropropyl 4-bromo-2-chloro-6-fluorophenyl ether; (4-Bromo-2-chloro-6-fluorophenyl)hexafluoroisopropyl ether; Hexafluoroisopropyl 4-bromo-2-chloro-6-fluorophenyl ether
EINECS	Contact for details

Quality Control

Our (4-Bromo-2-Chloro-6-Fluorophenyl)-1,1,2,3,3,3-Hexafluoropropyl Ether is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment supports compliance with REACH and other global regulatory frameworks for research and commercial use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in opaque or amber packaging during storage and handling.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Standard Grade)
Purity (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.