Description

1,3-Bis[(3-Fluorophenyl)-Phenyl-Methyl]Urea is a specialized organic compound featuring a urea core symmetrically substituted with fluorinated and non-fluorinated aromatic groups. This molecular architecture makes it a valuable intermediate for the development of advanced materials and active pharmaceutical ingredients (APIs), particularly where specific fluorine substitution patterns are required. It is primarily sought by research and development teams in the pharmaceutical, agrochemical, and specialty chemical industries for synthesis and screening applications.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders or requiring enhanced metabolic stability.
• Agrochemical Research: Used in the development of new pesticides and herbicides, where the fluorine atoms can improve biological activity and environmental persistence.
• Material Science Precursor: Acts as a monomer or cross-linking agent in the creation of specialty polymers, resins, or liquid crystals with tailored thermal and optical properties.
• Chemical Synthesis Reagent: Employed in organic synthesis for constructing complex urea-based frameworks in academic and industrial research settings.
• Biochemical Probe Development: Utilized in medicinal chemistry to create probes for studying enzyme inhibition or receptor binding mechanisms.

Basic Information

Item	Details
Product Name	1,3-Bis[(3-Fluorophenyl)-Phenyl-Methyl]Urea
CAS No.	160807-81-8
Molecular Formula	C27H20F2N2O
Molecular Weight	426.46 g/mol
Synonyms	1,3-Bis[(3-fluorophenyl)(phenyl)methyl]urea; 1,3-Bis[di(3-fluorophenyl)methyl]urea (common misnomer); Urea, N,N'-bis[(3-fluorophenyl)phenylmethyl]-; 1,3-Bis(α-phenyl-3-fluorobenzyl)urea; BFPU (abbreviation); (3-Fluorophenyl)(phenyl)methyl isocyanate dimer derivative; Symmetrical diaryl substituted urea derivative
EINECS	Contact for details

Quality Control

Our 1,3-Bis[(3-Fluorophenyl)-Phenyl-Methyl]Urea is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and heavy metals. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to ensure traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.