Description

2,2'-Dibromo-5,5',6,6',7,7',8,8'-Octahydro-1,1'-Binaphthalene is a specialized brominated binaphthyl derivative, a high-value intermediate prized for its rigid, chiral scaffold. This compound matters for its role in the synthesis of advanced materials and ligands for asymmetric catalysis, where its structure imparts critical steric and electronic properties. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors seeking to develop novel chiral compounds. The product is supplied under strict quality control to ensure batch-to-batch consistency for sensitive synthetic applications.

Application

• Pharmaceutical Intermediate: Serves as a key chiral building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in oncology and central nervous system (CNS) drug discovery.
• Catalyst & Ligand Synthesis: Used to construct sophisticated chiral phosphine or N-heterocyclic carbene (NHC) ligands for asymmetric hydrogenation and cross-coupling reactions.
• Advanced Material Precursor: Acts as a monomer or core unit in the development of chiral organic semiconductors, liquid crystals, and polymers with specific optical properties.
• Agrochemical Research: Employed in the creation of new chiral herbicides and fungicides where stereochemistry impacts biological activity.
• Academic & Industrial R&D: A valuable tool compound for methodological development in organic synthesis and stereochemistry studies.

Basic Information

Item	Detail
Product Name	2,2'-Dibromo-5,5',6,6',7,7',8,8'-Octahydro-1,1'-Binaphthalene
CAS No.	160456-37-1
Molecular Formula	C20H22Br2
Molecular Weight	414.20 g/mol
Synonyms	1,1'-Binaphthalene, 2,2'-dibromo-5,5',6,6',7,7',8,8'-octahydro-; 2,2'-Dibromooctahydro-1,1'-binaphthyl; Octahydro-2,2'-dibromo-1,1'-binaphthalene; H8-BINOL-2,2'-dibromide; 2,2'-Dibromo-H8-BINOL; Perhydro-2,2'-dibromo-1,1'-binaphthyl
EINECS	Contact for details

Quality Control

Our 2,2'-Dibromo-5,5',6,6',7,7',8,8'-Octahydro-1,1'-Binaphthalene is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC for purity and chiral purity assessment, to ensure it meets the high standards required for advanced synthetic applications. Certificates of Analysis (COA) documenting identity, purity, and impurity profiles are available upon request. We support cGMP compliance for pharmaceutical applications and can provide regulatory support documentation as needed.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container sealed under an inert atmosphere to prevent potential degradation. Store away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.