Description

6-Isocyanatoquinoline is a versatile and highly reactive aromatic isocyanate derivative, serving as a critical building block in advanced organic synthesis. Its primary value lies in its ability to introduce the quinoline pharmacophore and a reactive isocyanate group into target molecules, enabling the creation of novel compounds with tailored properties. This intermediate is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and materials science industries, particularly for developing active ingredients, functional polymers, and specialty chemicals.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in oncology and antiviral research where the quinoline scaffold is prevalent.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, leveraging its reactivity to create potent active ingredients.
• Polymer & Material Science: Serves as a monomer or cross-linking agent for producing high-performance polyurethanes, polyureas, and other specialty polymers with enhanced thermal or chemical resistance.
• Ligand & Catalyst Development: Utilized to synthesize complex ligands for metal-organic frameworks (MOFs) and catalysts for asymmetric synthesis.
• Dye & Pigment Manufacturing: Acts as an intermediate in the production of advanced quinoline-based dyes and functional colorants.
• Research & Development: A valuable tool in academic and industrial R&D for exploring new chemical entities and reaction pathways.

Basic Information

Product Name	6-Isocyanatoquinoline
CAS No.	160455-77-6
Molecular Formula	C10H6N2O
Molecular Weight	170.17 g/mol
Synonyms	6-Quinoline isocyanate; 6-Isocyanato-quinoline; Quinolin-6-yl isocyanate; Isocyanic acid, 6-quinolyl ester; 6-Isocyanatochinolin; 6-Quinolyl isocyanate; 160455-77-6; NSC 406156
EINECS	Contact for details

Quality Control

Our 6-Isocyanatoquinoline is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by FT-IR and NMR spectroscopy, to ensure it meets the high standards required for research and industrial synthesis. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its moisture-sensitive (hygroscopic) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.