Description

n-Boc-3-Amino-4-Chlorobenzoic Acid is a protected amino acid derivative that serves as a crucial synthetic intermediate in advanced organic chemistry. This compound is valued for its role in facilitating the controlled synthesis of complex molecules, particularly in peptide and pharmaceutical research. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly those containing substituted benzoic acid scaffolds.
• Peptide Chemistry: Used in solid-phase and solution-phase peptide synthesis as a protected amino acid component to introduce specific functional groups.
• Agrochemical Synthesis: Intermediate in the production of herbicides, fungicides, and other crop protection agents that require chlorinated aromatic structures.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Building block for synthesizing functionalized polymers and advanced organic materials with specific optical or electronic properties.
• Chemical Biology Probes: Used to create tagged molecules for studying biological pathways and protein interactions.

Basic Information

Product Name	n-Boc-3-Amino-4-Chlorobenzoic Acid
CAS No.	160450-12-4
Molecular Formula	C12H14ClNO4
Molecular Weight	271.70 g/mol
Synonyms	3-[(tert-Butoxycarbonyl)amino]-4-chlorobenzoic Acid; 4-Chloro-3-[(tert-butoxycarbonyl)amino]benzoic Acid; Boc-3-A-4-Cl-BA; tert-Butyl (5-chloro-2-carboxyphenyl)carbamate; 3-(Boc-amino)-4-chlorobenzoic Acid; 4-Chloro-3-(Boc-amino)benzoic Acid; 3-Amino-4-chlorobenzoic acid tert-butyl carbamate; 160450-12-4
EINECS	Contact for details

Quality Control

Our n-Boc-3-Amino-4-Chlorobenzoic Acid is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for assay and impurity profiling. Certificates of Analysis (COA) detailing purity, identity, and related substances are provided with every shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (HPLC, Area %)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.