Description

Samarium Sm 153 Lexidronam Pentasodium is a radiopharmaceutical complex specifically designed for targeted radiotherapy. This compound is critical for the palliative treatment of bone pain associated with metastatic skeletal lesions. It is primarily utilized by radiopharmacies, nuclear medicine departments, and specialized pharmaceutical manufacturers. The agent localizes to areas of high bone turnover, delivering localized radiation to provide significant pain relief.

Application

• Palliative Radiotherapy for Bone Metastases: Primary use in the management of pain from prostate, breast, and other cancers that have metastasized to the skeleton.
• Radiopharmaceutical Manufacturing: Serves as the active pharmaceutical ingredient (API) in the preparation of therapeutic radiopharmaceutical kits.
• Nuclear Medicine Research: Used in clinical studies and development of new therapeutic protocols for metastatic bone disease.
• Oncology Treatment Centers: Administered in hospital settings under controlled nuclear medicine protocols for patient care.
• Quality Control Reference Standard: Employed as a calibration standard in analytical laboratories for assay validation and purity testing.

Basic Information

Item	Details
Product Name	Samarium Sm 153 Lexidronam Pentasodium
CAS No.	160369-78-8
Molecular Formula	C22H18N3Na5O16P2153Sm
Molecular Weight	Contact for details
Synonyms	Samarium-153 EDTMP; 153Sm-EDTMP; Samarium (153Sm) Lexidronam; Quadramet® (Brand Name); Samarium Sm-153 Ethylenediaminetetramethylenephosphonate; 153Sm-EDTMP Pentasodium; Samarium-153 Ethylenediaminetetramethylenephosphonic Acid Pentasodium Salt
EINECS	Contact for details

Quality Control

Every batch of Samarium Sm 153 Lexidronam Pentasodium is manufactured and tested under strict quality systems. Our quality control procedures ensure compliance with current Good Manufacturing Practice (cGMP) guidelines relevant for radiopharmaceutical APIs. Release specifications include tests for radionuclidic purity, radiochemical purity, specific activity, and sterility where applicable. A comprehensive Certificate of Analysis (COA) is provided with each shipment, detailing all critical quality attributes.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature or as specified on the label. Due to its radioactive nature and specific chemical properties, handle and store in accordance with all local, national, and international regulations for radioactive materials. The product is strictly light-sensitive and must be protected from all light exposure during storage.

Specification

Item	Specification
Appearance	Clear, colorless to slightly yellow solution
Identification (Gamma Spectroscopy)	Complies
Radionuclidic Purity (153Sm)	≥ 99.9%
Radiochemical Purity (HPLC/TLC)	≥ 95.0%
Specific Activity	Contact for details
pH	7.0 - 8.5
Endotoxin (LAL)	< 175 EU/Vial
Sterility (Membrane Filtration)	Sterile

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.