Description

7-Propan-2-Yl-1,5,7-Triazabicyclo[4.4.0]Dec-5-Ene CAS NO 160172-95-2 is a highly versatile bicyclic guanidine compound, recognized for its exceptional utility as a strong, non-nucleophilic organic base. Its core value proposition lies in its ability to facilitate challenging deprotonation reactions and catalyze organic transformations under mild conditions, offering superior performance compared to traditional inorganic bases. This makes it an indispensable reagent for researchers and process chemists in the pharmaceutical, agrochemical, and specialty chemical industries, where precise control over reaction pathways is critical.

Application

• Pharmaceutical Synthesis: As a catalyst and base in the production of active pharmaceutical ingredients (APIs), particularly for complex heterocyclic compounds and fine chemical intermediates.
• Polymer Chemistry: Catalyst for the production of polyurethanes, polycarbonates, and other specialty polymers, enabling controlled polymerization reactions.
• Agrochemical Manufacturing: Key reagent in the synthesis of advanced herbicides, fungicides, and plant growth regulators.
• Organic Synthesis & Research: A powerful tool for deprotonating weak acids, promoting condensation reactions, and serving as a ligand or catalyst in metal-organic frameworks (MOFs).
• Chemical Intermediate: Used in the multi-step synthesis of complex organic molecules, dyes, and photoinitiators.
• Cross-Coupling Reactions: Acts as a base in palladium-catalyzed reactions such as Suzuki, Heck, and Sonogashira couplings.

Basic Information

Product Name	7-Propan-2-Yl-1,5,7-Triazabicyclo[4.4.0]Dec-5-Ene
CAS No.	160172-95-2
Molecular Formula	C9H16N4
Molecular Weight	180.25 g/mol
Synonyms	1,5,7-Triazabicyclo[4.4.0]dec-5-ene, 7-Isopropyl-; 7-Isopropyl-1,5,7-triazabicyclo[4.4.0]dec-5-ene; TBD (1,5,7-Triazabicyclo[4.4.0]dec-5-ene); 7-(Propan-2-yl)-1,5,7-triazabicyclo[4.4.0]dec-5-ene; 1,5,7-Triazabicyclo[4.4.0]dec-5-ene, 7-(1-methylethyl)-; Strong organic base TBD; Bicyclic Guanidine Base; 7-iPr-TBD
EINECS	Contact for details

Quality Control

Our 7-Propan-2-Yl-1,5,7-Triazabicyclo[4.4.0]Dec-5-Ene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements for research and industrial applications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to guarantee traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Due to its hygroscopic (moisture-sensitive) nature, store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry place. Recommended long-term storage temperature is 2-8°C. Keep the container tightly sealed in a dry and well-ventilated area, away from incompatible materials such as strong acids.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.