Description

Carbamic Acid, (1-Methyl-2-Nitroso-2-Oxoethyl)-, 1,1-Dimethylethyl Ester, (S)- is a specialized chiral intermediate of significant interest in advanced organic synthesis. Its value lies in its unique molecular architecture, featuring both a nitroso and a carbamate-protected functional group, which makes it a versatile building block for constructing complex, stereodefined molecules. This compound is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the research and development of new active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs.
• Agrochemical Synthesis: Used in the production of advanced, stereospecific pesticides and herbicides where specific chirality is crucial for biological activity.
• Organic Synthesis Research: Serves as a protected amino acid derivative or a nitroso-containing precursor in complex multi-step synthetic routes in academic and industrial R&D labs.
• Peptidomimetics Development: Employed in the design and synthesis of peptide analogs and mimetics for drug discovery applications.
• Ligand and Catalyst Preparation: Useful for constructing specialized chiral ligands or organocatalysts used in asymmetric synthesis.

Basic Information

Product Name	Carbamic Acid, (1-Methyl-2-Nitroso-2-Oxoethyl)-, 1,1-Dimethylethyl Ester, (S)-
CAS No.	160057-01-2
Molecular Formula	C9H16N2O4
Molecular Weight	216.24 g/mol
Synonyms	(S)-tert-Butyl 1-methyl-2-nitroso-2-oxoethylcarbamate; (S)-N-(tert-Butoxycarbonyl)-2-nitrosoalanine; (S)-Boc-2-nitrosoalanine; (S)-2-Nitrosoalanine tert-butyl ester; tert-Butyl (S)-(1-methyl-2-nitroso-2-oxoethyl)carbamate; (S)-N-Boc-2-nitrosoalanine; Boc-L-2-nitrosoalanine O-tert-butyl ester
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Every batch is characterized using advanced analytical techniques to confirm identity, purity, and chiral integrity. Certificates of Analysis (COA) detailing specific results for chiral purity, assay, and impurity profiles are available upon request. We adhere to strict quality management protocols suitable for R&D and cGMP-grade material production.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its sensitivity to oxidation, it is recommended to store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single unknown impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.