Description

Ethyl 2-Aminopent-4-Ynoate Hydrochloride is a versatile chiral building block and synthetic intermediate of significant importance in modern organic synthesis. Its value lies in the combination of an amine hydrochloride salt for stability and a terminal alkyne functionality, enabling diverse coupling and cyclization reactions. This compound is primarily needed by research institutions and pharmaceutical companies for the development of novel active pharmaceutical ingredients (APIs) and complex organic molecules.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new drug candidates, particularly in medicinal chemistry programs.
• Peptidomimetic Synthesis: Used in the construction of peptide analogs and constrained scaffolds to modulate biological activity and stability.
• Heterocyclic Chemistry: Serves as a precursor for the synthesis of various nitrogen- and oxygen-containing heterocycles via cycloaddition or ring-closing reactions.
• Click Chemistry: The terminal alkyne group makes it an ideal substrate for copper-catalyzed azide-alkyne cycloaddition (CuAAC) reactions to create triazole linkages.
• Ligand and Catalyst Development: Employed in the synthesis of novel chiral ligands and organocatalysts for asymmetric synthesis.
• Agrochemical Research: Used as a building block in the discovery and synthesis of new crop protection agents and herbicides.

Basic Information

Product Name	Ethyl 2-Aminopent-4-Ynoate Hydrochloride
CAS No.	160009-06-3
Molecular Formula	C7H12ClNO2
Molecular Weight	177.63 g/mol
Synonyms	Ethyl 2-Aminopent-4-ynoate Hydrochloride; 2-Aminopent-4-ynoic Acid Ethyl Ester Hydrochloride; 4-Pentynoic acid, 2-amino-, ethyl ester, hydrochloride; Ethyl 2-amino-4-pentynoate hydrochloride; (RS)-Ethyl 2-amino-4-pentynoate hydrochloride; Ethyl 2-aminopent-4-ynoate HCl; 160009-06-3
EINECS	Contact for details

Quality Control

Our Ethyl 2-Aminopent-4-Ynoate Hydrochloride is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.