Description

1-[4-(4-Chlorophenyl)-1,3-Thiazol-2-Yl]-5-(Trifluoromethyl)-1H-Pyrazole-4-Carboxylic Acid CAS NO 159885-82-2 is a high-purity, advanced pharmaceutical intermediate characterized by its unique heterocyclic structure combining pyrazole, thiazole, and trifluoromethyl functionalities. This compound is of significant commercial value for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing new therapeutic and crop protection agents.

Application

• Pharmaceutical Intermediate: A key precursor in the research and synthesis of novel drug candidates, particularly in therapeutic areas requiring complex heterocyclic scaffolds.
• Agrochemical Synthesis: Serves as a vital building block for developing new-generation pesticides and herbicides, leveraging the bioactivity of the thiazole and pyrazole rings.
• Chemical Research & Development: Used in academic and industrial R&D for exploring structure-activity relationships (SAR) and creating new chemical libraries for screening.
• Active Pharmaceutical Ingredient (API) Manufacturing: Employed in the scaled-up production process of specific APIs where this moiety is integral to the final molecule's activity.
• Material Science: Potential application in the synthesis of specialized organic materials and ligands for catalytic systems.

Basic Information

Product Name	1-[4-(4-Chlorophenyl)-1,3-Thiazol-2-Yl]-5-(Trifluoromethyl)-1H-Pyrazole-4-Carboxylic Acid
CAS No.	159885-82-2
Molecular Formula	C14H7ClF3N3O2S
Molecular Weight	373.74 g/mol
Synonyms	1-[4-(4-Chlorophenyl)-1,3-thiazol-2-yl]-5-(trifluoromethyl)-1H-pyrazole-4-carboxylic acid; 5-(Trifluoromethyl)-1-[4-(4-chlorophenyl)-1,3-thiazol-2-yl]-1H-pyrazole-4-carboxylic acid; 1H-Pyrazole-4-carboxylic acid, 1-[4-(4-chlorophenyl)-1,3-thiazol-2-yl]-5-(trifluoromethyl)-; CAS 159885-82-2; 4-(4-Chlorophenyl)-2-[4-(carboxy)-5-(trifluoromethyl)pyrazol-1-yl]thiazole
EINECS	Contact for details

Quality Control

Our production of 1-[4-(4-Chlorophenyl)-1,3-Thiazol-2-Yl]-5-(Trifluoromethyl)-1H-Pyrazole-4-Carboxylic Acid adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific customer or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. The container must be kept tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.