Description

Boc-D-Dap(Boc)-Oh Dcha is a protected amino acid derivative, specifically a Boc-protected D-diaminopropionic acid salt with dicyclohexylamine. This compound is a crucial chiral building block in the synthesis of complex peptides and peptidomimetics, offering high stereochemical purity and stability for demanding applications. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel therapeutic agents, diagnostic tools, and advanced biochemical research.

Application

• Pharmaceutical Intermediates: A key chiral synthon in the synthesis of peptide-based drugs, antibiotics, and enzyme inhibitors.
• Peptide Synthesis: Used in solid-phase and solution-phase peptide synthesis (SPPS) to incorporate D-diaminopropionic acid residues with orthogonal protection.
• Proteomics Research: Employed in the design and construction of custom peptides for studying protein-protein interactions and structure-activity relationships (SAR).
• Bioconjugation: Serves as a linker or spacer molecule in the preparation of antibody-drug conjugates (ADCs) and other bioconjugates.
• Chemical Biology: Utilized to create peptide libraries and modified peptides for probing biological pathways and developing new diagnostics.
• Agrochemical Research: Potential intermediate in the development of bioactive peptides for crop protection agents.

Basic Information

Product Name	Boc-D-Dap(Boc)-Oh Dcha
CAS No.	159652-30-9
Molecular Formula	C24H45N3O6
Molecular Weight	471.64 g/mol
Synonyms	Nα,Nβ-Bis(tert-butoxycarbonyl)-D-diaminopropionic Acid Dicyclohexylamine Salt; (R)-2,3-Bis((tert-butoxycarbonyl)amino)propionic Acid DCHA Salt; Boc-D-Dap(Boc)-OH·DCHA; D-Dap(Boc)2-OH DCHA Salt; Boc-D-2,3-Diaminopropionic Acid(Boc) Dicyclohexylamine Salt; (R)-3-Amino-2-((tert-butoxycarbonyl)amino)propanoic Acid DCHA Salt (protected form); N-Boc-D-2,3-diaminopropanoic Acid N-Boc Derivative DCHA Salt
EINECS	Contact for details

Quality Control

Our Boc-D-Dap(Boc)-Oh Dcha is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis for enantiomeric excess, and NMR for structural confirmation, to ensure compliance with research and cGMP-grade standards where applicable. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting identity, purity, and specific impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as indicated on the label or COA. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity. Keep container tightly sealed in a desiccated environment after opening.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% ee
Water Content (KF)	≤0.5%
Heavy Metals	≤10 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.