Description

1'-(1-(3-Iodobenzyl)-4-Hydroxypiperidin-3-Yl)-3,4-Dihydrospiro(Naphthalene-1(2H),4'-Piperidine) is a complex, high-purity spirocyclic organic compound featuring a piperidine-naphthalene core structure with an iodobenzyl substituent. This compound matters as a sophisticated pharmaceutical intermediate or research chemical critical for the synthesis and development of novel bioactive molecules, particularly in central nervous system (CNS) and receptor-targeted drug discovery. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical and biotechnology industries, as well as by academic researchers exploring new chemical entities.

Application

• Pharmaceutical Intermediate: Key building block in the multi-step synthesis of potential drug candidates, especially those targeting neurological receptors.
• Medicinal Chemistry Research: Used as a core scaffold or a derivatization starting point for structure-activity relationship (SAR) studies in drug discovery programs.
• Chemical Biology Probe: Serves as a tool compound for investigating biological pathways and protein-ligand interactions due to its specific structural features.
• Process Chemistry Development: Employed in scaling up and optimizing synthetic routes for the production of advanced active pharmaceutical ingredients (APIs).
• Reference Standard: Used as a high-purity analytical standard for quality control and method development in analytical laboratories.

Basic Information

Product Name	1'-(1-(3-Iodobenzyl)-4-Hydroxypiperidin-3-Yl)-3,4-Dihydrospiro(Naphthalene-1(2H),4'-Piperidine)
CAS No.	158628-72-9
Molecular Formula	C27H33IN2O
Molecular Weight	528.47 g/mol
Synonyms	1'-[1-[(3-Iodophenyl)methyl]-4-hydroxypiperidin-3-yl]-3,4-dihydrospiro[naphthalene-1(2H),4'-piperidine]; 1'-(1-(3-Iodobenzyl)-4-hydroxypiperidin-3-yl)-3,4-dihydrospiro[naphthalene-1(2H),4'-piperidine]; 158628-72-9; Spiro[naphthalene-1(2H),4'-piperidine], 1'-[1-[(3-iodophenyl)methyl]-4-hydroxy-3-piperidinyl]-3,4-dihydro-; 3,4-Dihydro-1'-[1-[(3-iodophenyl)methyl]-4-hydroxy-3-piperidinyl]spiro[naphthalene-1(2H),4'-piperidine]; 1'-(1-(3-Iodobenzyl)-4-hydroxypiperidin-3-yl)-3,4-dihydro-2H-spiro[naphthalene-1,4'-piperidine]
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Every batch is characterized using advanced analytical techniques to confirm identity, purity, and consistency. Certificates of Analysis (COA) detailing specific results for each lot are available upon request. We adhere to a cGMP-compliant quality management system suitable for pharmaceutical research applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep the container sealed to protect from moisture and contamination.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.