Description

1'-(1-(3-Iodobenzyl)-4-Hydroxypiperidin-3-Yl)Spiro(1H-Indene-1,4'-Piperidine) is a sophisticated spirocyclic organic compound of significant interest in advanced pharmaceutical research and development. Its complex molecular architecture, featuring a piperidine-indene core, makes it a valuable intermediate for synthesizing novel bioactive molecules. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical and biotechnology sectors. The CAS number for this substance is 158628-37-6.

Application

This high-purity chemical intermediate is designed for specialized research and development applications, particularly in the life sciences.

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of potential new chemical entities (NCEs) for drug discovery programs.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to explore and optimize biological activity profiles.
• Process Chemistry Development: Employed in scaling up synthetic routes for active pharmaceutical ingredients (APIs) under Good Manufacturing Practice (GMP) conditions.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and development services for the pharmaceutical industry.
• Academic Research: Utilized in university and institutional labs for fundamental studies in organic synthesis and heterocyclic chemistry.

Basic Information

Product Name	1'-(1-(3-Iodobenzyl)-4-Hydroxypiperidin-3-Yl)Spiro(1H-Indene-1,4'-Piperidine)
CAS No.	158628-37-6
Molecular Formula	C25H29IN2O
Molecular Weight	500.42 g/mol
Synonyms	1'-[1-[(3-Iodophenyl)methyl]-4-hydroxy-3-piperidinyl]spiro[1H-indene-1,4'-piperidine]; Spiro[1H-indene-1,4'-piperidine], 1'-[1-[(3-iodophenyl)methyl]-4-hydroxy-3-piperidinyl]-; 1'-(1-(3-Iodobenzyl)-4-hydroxypiperidin-3-yl)spiro[indene-1,4'-piperidine]; 158628-37-6; AKOS024434493; CS-0426647; FT-0665787; 1'-(1-(3-Iodobenzyl)-4-hydroxypiperidin-3-yl)spiro[1H-indene-1,4'-piperidine]
EINECS	Contact for details

Quality Control

We supply 1'-(1-(3-Iodobenzyl)-4-Hydroxypiperidin-3-Yl)Spiro(1H-Indene-1,4'-Piperidine) to meet the stringent requirements of research and development. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) are available upon request, detailing purity, identity, and impurity profiles. We can support development with material produced under GMP-like conditions for advanced non-clinical and clinical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). The container should be kept tightly sealed in a dry environment to minimize exposure to moisture. For long-term storage, consider inert atmosphere conditions.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.