Description

(1R,2R)-(-)-2-Amino-1-Cyclopentanecarboxylic Acid Hydrochloride is a high-purity chiral building block and a derivative of the non-proteinogenic amino acid, (1R,2R)-2-aminocyclopentanecarboxylic acid. This compound matters as a critical intermediate in the asymmetric synthesis of pharmaceuticals and bioactive molecules, offering precise stereochemical control. It is primarily needed by research institutions and manufacturers in the pharmaceutical industry for developing novel drug candidates, particularly in the areas of protease inhibitors and peptidomimetics.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new active pharmaceutical ingredients (APIs), especially protease inhibitors.
• Peptidomimetics Research: Used to construct constrained peptide analogs to enhance metabolic stability and bioavailability in drug design.
• Asymmetric Synthesis: Serves as a building block in stereoselective organic synthesis to introduce the (1R,2R) cyclopentane scaffold.
• Biochemical Research: Employed in studies of enzyme-substrate interactions and as a standard in analytical method development.
• Ligand Synthesis: Utilized in the preparation of chiral ligands for catalysis and metal complexation.

Basic Information

Product Name	(1R,2R)-(-)-2-Amino-1-Cyclopentanecarboxylic Acid Hydrochloride
CAS No.	158414-44-9
Molecular Formula	C6H12ClNO2
Molecular Weight	165.62 g/mol
Synonyms	(1R,2R)-2-Aminocyclopentanecarboxylic Acid Hydrochloride; (1R,2R)-ACPC HCl; (1R,2R)-2-Amino-1-cyclopentanecarboxylic acid hydrochloride; (1R,2R)-2-Aminocyclopentane-1-carboxylic Acid Hydrochloride; (1R,2R)-(-)-2-Amino-1-cyclopentancecarboxylic acid hydrochloride; (1R,2R)-2-Amino-cyclopentanecarboxylic acid hydrochloride; (1R,2R)-2-Aminocyclopentane carboxylic acid HCl
EINECS	Contact for details

Quality Control

Our (1R,2R)-(-)-2-Amino-1-Cyclopentanecarboxylic Acid Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure compliance with high-grade standards for research and pharmaceutical applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% ee
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.