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Sodium Acetylated Hyaluronate CAS NO 158254-23-0


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CAS No.:158254-23-0

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

Sodium Acetylated Hyaluronate is a chemically modified derivative of hyaluronic acid, engineered for enhanced stability and unique functional properties. This modification significantly improves its lipophilicity and skin adhesion, making it a superior ingredient for advanced cosmetic and biomedical formulations. It is primarily sought by manufacturers in the premium skincare, nutraceutical, and pharmaceutical industries for developing high-performance anti-aging, moisturizing, and dermal filler products.

Application

  • Premium Skincare Products: A key active ingredient in serums, creams, and masks for long-lasting hydration, improved skin elasticity, and wrinkle reduction.
  • Injectable Dermal Fillers: Used in biomedical aesthetics for its enhanced viscoelasticity and prolonged residence time in the skin compared to standard hyaluronic acid.
  • Advanced Wound Healing: Incorporated into hydrogel dressings and scaffolds to promote tissue regeneration and moisture retention.
  • Ophthalmic Solutions: Utilized in lubricating eye drops and surgical viscoelastic products due to its mucoadhesive properties.
  • Nutraceutical Supplements: An ingredient in oral supplements targeting joint health and skin hydration from within.
  • Hair Care Formulations: Added to conditioners and treatments to improve hair moisture, shine, and manageability.

Basic Information

Product Name Sodium Acetylated Hyaluronate
CAS No. 158254-23-0
Molecular Formula (C14H20NNaO11)n
Molecular Weight Variable (Polymer)
Synonyms Acetylated Sodium Hyaluronate; AcHA; Acetyl Hyaluronic Acid Sodium Salt; Sodium Hyaluronate Acetate; HA-Ac; N-Acetylhyaluronan Sodium Salt; Hyaluronic Acid Acetyl Ester Sodium Salt
EINECS Contact for details

Quality Control

Our Sodium Acetylated Hyaluronate is produced under strict quality management systems. Each batch is tested to ensure it meets stringent specifications for purity, acetyl substitution degree, molecular weight, and microbiological safety. Certificates of Analysis (COA) are provided with every shipment, detailing key parameters such as assay, heavy metals, residual solvents, and endotoxin levels where applicable.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C for long-term stability. This product is hygroscopic (moisture-sensitive) and must be kept in a low-humidity environment. After opening, seal the container immediately under an inert atmosphere such as nitrogen to prevent moisture uptake and degradation.

Specification

Item Specification
Appearance White to off-white fibrous solid or powder
Identification (IR) Conforms
Assay (as Sodium Hyaluronate) ≥ 95.0%
Degree of Acetylation 10 - 30%
Molecular Weight 50 kDa - 2,000 kDa (Customizable)
pH (1% Solution) 6.0 - 8.0
Loss on Drying ≤ 10.0 %
Protein Content ≤ 0.1 %
Heavy Metals (as Pb) ≤ 10 ppm
Microbial Count ≤ 100 CFU/g
Endotoxin (for injectable grade) < 0.05 EU/mg

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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Each batch undergoes strict QC, accompanied by COA, MSDS, and full compliance with international standards.

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