Description

5,7-Dichloro-4-Hydroxy-Quinoline-2-Carboxylic Acid Ethyl Ester is a high-purity, synthetically valuable quinoline derivative. This compound serves as a critical pharmaceutical intermediate, particularly in the synthesis of advanced active pharmaceutical ingredients (APIs) and complex organic molecules. It is essential for research and development chemists, process development scientists, and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries seeking reliable, high-quality building blocks for complex synthesis.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel quinoline-based drug candidates, including potential antimicrobial and anticancer agents.
• Agrochemical Synthesis: Used in the research and development of advanced crop protection agents and pesticides.
• Organic Synthesis Reagent: Serves as a versatile precursor for constructing complex heterocyclic compounds in academic and industrial research laboratories.
• Material Science Research: Investigated as a monomer or precursor for the development of functional organic materials and dyes.
• Chemical Reference Standard: Employed as an analytical standard for quality control and method development in pharmaceutical analysis.

Basic Information

Product Name	5,7-Dichloro-4-Hydroxy-Quinoline-2-Carboxylic Acid Ethyl Ester
CAS No.	157848-08-3
Molecular Formula	C₁₂H₉Cl₂NO₃
Molecular Weight	286.11 g/mol
Synonyms	Ethyl 5,7-dichloro-4-hydroxyquinoline-2-carboxylate; 5,7-Dichloro-4-hydroxy-2-quinolinecarboxylic acid ethyl ester; 4-Hydroxy-5,7-dichloroquinoline-2-carboxylic acid ethyl ester; 2-Quinolinecarboxylic acid, 5,7-dichloro-4-hydroxy-, ethyl ester; Ethyl 5,7-dichloro-4-oxo-1,4-dihydroquinoline-2-carboxylate
EINECS	Contact for details

Quality Control

Our 5,7-Dichloro-4-Hydroxy-Quinoline-2-Carboxylic Acid Ethyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for pharmaceutical intermediate applications. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This product is easily oxidized and should be handled and stored under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.