Description

4-(3-Isothiocyanate-4-Methoxyphenyl)-6,6''-Bis(N,n-Di-(Carboxymethylaminomethyl))-2,2'-6',2''-Terpyridine is a sophisticated, multifunctional chelating ligand designed for advanced coordination chemistry and material science applications. Its core value lies in its unique molecular architecture, which incorporates a terpyridine backbone for strong metal ion binding, coupled with an isothiocyanate group and multiple carboxymethylaminomethyl arms for versatile conjugation and enhanced chelation properties. This compound is essential for researchers and manufacturers in the fields of luminescent materials, molecular sensors, and catalysis, where precise control over metal-ligand interactions is critical. Its design facilitates the development of novel functional complexes with tailored photophysical and chemical behaviors.

Application

• Luminescent Material Synthesis: As a key ligand for constructing lanthanide (e.g., Eu³⁺, Tb³⁺) or transition metal complexes used in OLEDs, bio-imaging probes, and security inks.
• Molecular Sensor Development: For creating highly selective and sensitive chemosensors for detecting metal ions (e.g., Zn²⁺, Cu²⁺) or anions in analytical and environmental monitoring applications.
• Catalysis Research: Serving as a supporting ligand for homogeneous catalysts in organic synthesis and polymerization reactions, where its chelating ability can stabilize active metal centers.
• Radiopharmaceuticals & Medical Imaging: Potential use in chelator design for binding diagnostic or therapeutic radiometals (e.g., ⁶⁸Ga, ¹⁷⁷Lu) in targeted drug delivery systems.
• Surface Functionalization: The isothiocyanate group allows for covalent attachment to amine-functionalized surfaces (nanoparticles, polymers, glass), creating modified interfaces for sensing or separation.
• Supramolecular Chemistry: As a building block for constructing complex molecular architectures, such as metallo-supramolecular polymers or cages.

Basic Information

Item	Details
Product Name	4-(3-Isothiocyanate-4-Methoxyphenyl)-6,6''-Bis(N,n-Di-(Carboxymethylaminomethyl))-2,2'-6',2''-Terpyridine
CAS No.	157837-77-9
Molecular Formula	C₃₇H₃₈N₈O₈S
Molecular Weight	754.81 g/mol
Synonyms	4'-(3-Isothiocyanato-4-methoxyphenyl)-6,6''-bis[bis(carboxymethyl)aminomethyl]-2,2':6',2''-terpyridine; 4-(3-Isothiocyanato-4-methoxyphenyl)-6,6''-bis[N,N-bis(carboxymethyl)aminomethyl]-2,2':6',2''-terpyridine; Terpyridine-Isothiocyanate-DOTA Analogue; Multifunctional Terpyridine Ligand; ITC-m-Terpy-DOTA Derivative; 4'-(4-Methoxy-3-isothiocyanatophenyl)-6,6''-bis(carboxymethylaminomethyl)-2,2':6',2''-terpyridine; Bis-DOTA-aminomethyl-terpyridine isothiocyanate; Contact for details on additional trade names.
EINECS	Contact for details

Quality Control

Our production of 4-(3-Isothiocyanate-4-Methoxyphenyl)-6,6''-Bis(N,n-Di-(Carboxymethylaminomethyl))-2,2'-6',2''-Terpyridine adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity for research and development purposes. Each lot undergoes comprehensive analytical characterization, including HPLC for purity assessment and structural confirmation via NMR and mass spectrometry. We provide a detailed Certificate of Analysis (COA) with every shipment, documenting key specifications. For custom synthesis or specific purity grades (e.g., >95%, >98%), please contact our technical team to discuss your requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. For long-term storage, consider storing at 2-8°C.

Specification

Item	Specification
Appearance	Off-white to light yellow solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 2.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.