Description

8-Iodonaphthalene-1-Carbonitrile is a versatile halogenated naphthalene derivative that serves as a critical synthetic intermediate in advanced organic chemistry. This compound matters for its unique reactivity profile, combining an electron-withdrawing cyano group with a reactive iodine atom, enabling selective cross-coupling and functionalization reactions. Pharmaceutical, agrochemical, and advanced materials researchers need it for constructing complex polycyclic aromatic frameworks and developing novel active ingredients.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in oncology and CNS research.
• Agrochemical Synthesis: Used in creating advanced herbicides, fungicides, and plant growth regulators with enhanced efficacy.
• Material Science Precursor: Serves as a monomer or precursor for organic semiconductors, liquid crystals, and conductive polymers.
• Cross-Coupling Reactions: Essential substrate for palladium-catalyzed reactions like Suzuki, Stille, and Sonogashira couplings to form biaryl systems.
• Ligand and Catalyst Development: Used to synthesize novel phosphine or nitrogen-based ligands for asymmetric catalysis.
• Fluorescent Dye and Sensor Synthesis: Building block for developing naphthalene-based fluorophores and chemosensors.
• Academic and R&D: Fundamental reagent for methodological studies in synthetic organic chemistry laboratories.
• Polymer Modification: Functional agent for introducing aromatic and cyano groups into polymer backbones to modify thermal and optical properties.

Basic Information

Product Name	8-Iodonaphthalene-1-Carbonitrile
CAS No.	157735-41-6
Molecular Formula	C11H6IN
Molecular Weight	279.08 g/mol
Synonyms	1-Cyano-8-iodonaphthalene; 8-Iodo-1-naphthonitrile; 1-Naphthonitrile, 8-iodo-; 8-Iodonaphthalene-1-carbonitrile; 157735-41-6; 8-Iodo-1-cyanonaphthalene; 8-Iodo-1-naphthalenecarbonitrile
EINECS	Contact for details

Quality Control

Our 8-Iodonaphthalene-1-Carbonitrile is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for purity assessment and NMR for structural confirmation, to meet the stringent requirements of research and development applications. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to guarantee traceability and compliance with your internal quality standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be amber glass or opaque to prevent degradation.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Meets ICH guidelines
Water Content (KF)	< 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.