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4-Chloro-3-Quinolinesulfonylchloride CAS NO 157494-40-1


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CAS No.:157494-40-1

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

4-Chloro-3-Quinolinesulfonylchloride is a key bifunctional chemical intermediate featuring both a reactive sulfonyl chloride and a chloro-substituted quinoline ring. This compound matters for its versatility in synthesizing more complex sulfonamide derivatives, which are crucial in the development of active pharmaceutical ingredients (APIs) and advanced agrochemicals. It is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for constructing novel molecular scaffolds.

Application

  • Pharmaceutical Intermediate: A critical building block for the synthesis of novel sulfonamide-based drug candidates, particularly in antimicrobial and anticancer research.
  • Agrochemical Synthesis: Used in the development of new herbicides and fungicides, leveraging the bioactive quinoline core.
  • Organic Synthesis Reagent: Serves as a versatile reagent for introducing the 3-quinolinesulfonyl moiety into target molecules in research and development.
  • Dye and Pigment Intermediate: Employed in the production of specialized quinoline-based dyes and functional pigments.
  • Material Science Research: Utilized in the creation of functionalized polymers or metal-organic frameworks (MOFs) with specific sulfonamide ligands.

Basic Information

Product Name 4-Chloro-3-Quinolinesulfonylchloride
CAS No. 157494-40-1
Molecular Formula C9H5Cl2NO2S
Molecular Weight 278.11 g/mol
Synonyms 4-Chloro-3-quinolinesulfonyl chloride; 3-Quinolinesulfonyl chloride, 4-chloro-; 4-Chloroquinoline-3-sulfonyl chloride; 157494-40-1; 4-Chloro-quinoline-3-sulfonyl chloride
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Quality Control

Our 4-Chloro-3-Quinolinesulfonylchloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets the high standards required for synthetic applications. Certificates of Analysis (COA) with detailed specifications are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under dry conditions to prevent degradation.

Specification

Item Specification
Appearance White to off-white crystalline powder
Identification (IR) Conforms to structure
Purity (HPLC) ≥ 98.0%
Loss on Drying ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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