Description

1H-Thieno[3,4-D]Imidazole-4-Pentanamide, Hexahydro-2-Oxo-n-(4-Pyridinylmethyl)-, (3As,4S,6Ar)- CAS NO 157446-76-9 is a high-purity, complex heterocyclic compound featuring a fused thienoimidazole core. This specialized chemical is a critical advanced pharmaceutical intermediate (API) and a valuable scaffold in medicinal chemistry research. It is primarily sought after by pharmaceutical R&D teams and fine chemical manufacturers for the development of novel therapeutic agents.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex drug candidates, particularly those targeting neurological or metabolic pathways.
• Medicinal Chemistry Research: Serves as a core scaffold for structure-activity relationship (SAR) studies and the design of new chemical entities (NCEs).
• Bioconjugation & Probe Development: Used in the creation of biochemical probes and labeled compounds for diagnostic or research applications.
• Organic Synthesis: Employed in advanced organic synthesis to construct complex polycyclic frameworks with potential biological activity.
• Reference Standard: Supplied as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.

Basic Information

Product Name	1H-Thieno[3,4-D]Imidazole-4-Pentanamide, Hexahydro-2-Oxo-n-(4-Pyridinylmethyl)-, (3As,4S,6Ar)-
CAS No.	157446-76-9
Molecular Formula	C16H22N4O2S
Molecular Weight	334.44 g/mol
Synonyms	(3aS,4S,6aR)-Hexahydro-2-oxo-1H-thieno[3,4-d]imidazole-4-pentanamide, N-(4-Pyridinylmethyl)-; BIOTIN-PYRIDYL ANALOG; 4-PYRIDYLMETHYLAMIDE OF D-BIOTIN; N-(4-PYRIDYLMETHYL)-D-BIOTINAMIDE; D-BIOTIN 4-PYRIDYLMETHYLAMIDE; (3aS,4S,6aR)-Hexahydro-2-oxo-N-(pyridin-4-ylmethyl)-1H-thieno[3,4-d]imidazole-4-pentanamide
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management systems. Every batch undergoes comprehensive analytical characterization to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing specifications such as assay (HPLC), chiral purity, and impurity profiles are provided with each shipment. We support development and commercial projects requiring material produced under GMP-like conditions upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept in a desiccated environment to prevent moisture uptake, which may affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.