Description

5-(tert-Butyl)-2-Hydroxyisophthalic Acid is a high-purity, multifunctional aromatic dicarboxylic acid derivative. This compound is valued for its unique structural features, including a sterically hindered tert-butyl group and a phenolic hydroxyl group, which make it a versatile intermediate in advanced organic synthesis. It is primarily sought by R&D chemists and process engineers in the pharmaceutical, agrochemical, and specialty polymer industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly those requiring rigid, functionalized aromatic cores.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and plant growth regulators where its substituted isophthalate structure imparts specific biological activity.
• Ligand and Chelator Precursor: Serves as a starting material for synthesizing specialized ligands used in catalysis and metal ion sequestration.
• Polymer Modifier: Incorporated into high-performance polymers, such as polyesters and polyamides, to modify thermal stability, solubility, and mechanical properties.
• Advanced Material Research: Employed in the development of organic frameworks, dyes, and photoactive materials in academic and industrial R&D settings.
• Fine Chemical Synthesis: A versatile synthon for creating complex, multi-functional organic molecules in custom synthesis projects.

Basic Information

Product Name	5-(tert-Butyl)-2-Hydroxyisophthalic Acid
CAS No.	157436-33-4
Molecular Formula	C12H14O5
Molecular Weight	238.24 g/mol
Synonyms	2-Hydroxy-5-tert-butylisophthalic Acid; 5-tert-Butyl-2-hydroxybenzene-1,3-dicarboxylic Acid; 1,3-Benzenedicarboxylic acid, 5-(1,1-dimethylethyl)-2-hydroxy-; 5-(1,1-Dimethylethyl)-2-hydroxy-1,3-benzenedicarboxylic Acid; 5-tert-Butyl-2-hydroxy-1,3-benzenedicarboxylic Acid; 5-(tert-Butyl)-2-hydroxyisophthalic acid; 2-Hydroxy-5-(tert-butyl)isophthalic Acid
EINECS	Contact for details

Quality Control

Our production of 5-(tert-Butyl)-2-Hydroxyisophthalic Acid adheres to strict quality management protocols. Every batch is subjected to comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets precise customer specifications. Certificates of Analysis (COA) documenting all critical quality attributes are available upon request, supporting your regulatory and quality assurance needs.

Storage

Preserve in a tightly closed container, protected from light. Due to its hygroscopic nature, store in a cool, dry place at a controlled room temperature (15-25°C) with low humidity. For long-term storage, consider the use of desiccants or an inert atmosphere to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.