Description

5,11,17,23-Tetra-T-Butyl-25,26,27,28-Tetrahydroxycalix-4-Arene is a functionalized calixarene derivative, a key member of the supramolecular chemistry building blocks. This compound matters for its pre-organized, cup-shaped molecular cavity, which enables selective binding and complexation of ions and neutral molecules. It is primarily needed by researchers and manufacturers in the fields of chemical sensing, catalysis, and advanced material science for developing host-guest systems and molecular recognition platforms.

Application

• Supramolecular Host-Guest Chemistry: Acts as a molecular receptor or building block for the construction of complex molecular architectures and capsules.
• Ion-Selective Sensors & Extraction: Utilized in the development of selective electrodes, membrane transporters, and separation technologies for metal ions.
• Catalysis & Enzyme Mimics: Serves as a scaffold for constructing artificial enzymes (biomimetics) and catalysts with tailored active sites.
• Advanced Material Synthesis: Incorporated into polymers, dendrimers, and nanomaterials to impart specific recognition or self-assembly properties.
• Pharmaceutical & Analytical Chemistry: Used in drug delivery system research and as a stationary phase modifier in chromatography for chiral or selective separations.
• Nanotechnology & Molecular Machines: Functions as a foundational component in the design of molecular switches, shuttles, and other nanoscale devices.

Basic Information

Product Name	5,11,17,23-Tetra-T-Butyl-25,26,27,28-Tetrahydroxycalix-4-Arene
CAS No.	157432-87-6
Molecular Formula	C44H56O4
Molecular Weight	648.92 g/mol
Synonyms	p-tert-Butylcalix[4]arene; 5,11,17,23-Tetra-tert-butyl-25,26,27,28-tetrahydroxycalix[4]arene; Calix[4]arene-tetraol, p-tert-Butyl-; Tetra-p-tert-butylcalix[4]arene; 4-tert-Butylcalix[4]arene; 25,26,27,28-Tetrahydroxy-5,11,17,23-tetra-tert-butylcalix[4]arene; p-t-Butylcalix[4]arene; Cone-p-tert-butylcalix[4]arene
EINECS	Contact for details

Quality Control

Our 5,11,17,23-Tetra-T-Butyl-25,26,27,28-Tetrahydroxycalix-4-Arene is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and melting point determination, to ensure high purity and structural integrity consistent with research-grade standards. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at room temperature (15-25°C). This compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	342 - 346 °C
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.