Description

5-Pyrimidinecarboxylicacid,4-Methyl- CAS NO 157335-92-7 is a high-purity pyrimidine derivative, a crucial heterocyclic building block in advanced organic synthesis. Its value lies in its role as a versatile intermediate for constructing complex molecular architectures, particularly in the development of active pharmaceutical ingredients (APIs). This compound is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to innovate new compounds with targeted biological activity.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of novel drug candidates, particularly in antiviral, anticancer, and anti-inflammatory therapeutic areas.
• Agrochemical Synthesis: Used in the production of advanced pesticides, herbicides, and fungicides where the pyrimidine core imparts specific biological activity.
• Ligand & Catalyst Development: Serves as a precursor for creating specialized ligands used in catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of organic electronic materials, dyes, and photoactive compounds.
• Custom Synthesis & Contract Manufacturing: A fundamental building block for custom chemical synthesis services catering to R&D and pilot-scale production.
• Academic & Institutional Research: Used in universities and research institutes for methodological studies and the exploration of new chemical reactions involving functionalized pyrimidines.

Basic Information

Product Name	5-Pyrimidinecarboxylicacid,4-Methyl-
CAS No.	157335-92-7
Molecular Formula	C6H6N2O2
Molecular Weight	138.12 g/mol
Synonyms	4-Methylpyrimidine-5-carboxylic acid; 4-Methyl-5-pyrimidinecarboxylic acid; 5-Carboxy-4-methylpyrimidine; 4-Methyl-5-carboxypyrimidine; 4-Methylpyrimidine-5-carboxylate; 5-Pyrimidinecarboxylic acid, 4-methyl-; 4-Methyl-5-pyrimidine carboxylic acid
EINECS	Contact for details

Quality Control

Our production of 5-Pyrimidinecarboxylicacid,4-Methyl- adheres to stringent in-process controls and final release testing to ensure batch-to-batch consistency and high purity. We employ advanced analytical techniques including HPLC, GC, and NMR for comprehensive characterization. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment. Our quality management system supports compliance with cGMP and ISO standards for reliable supply to regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.