Description

Glcnac-3S,6S,2Na is a high-purity, sulfated monosaccharide derivative, specifically the disodium salt of 3,6-di-O-sulfo-N-acetyl-D-glucosamine. This compound is a critical biochemical reagent and building block for advanced glycosaminoglycan (GAG) research and synthesis. It is essential for scientists and manufacturers in the pharmaceutical and life science sectors who require well-defined, structurally precise carbohydrate intermediates. Its defined sulfation pattern makes it invaluable for studying carbohydrate-protein interactions and developing novel therapeutics.

Application

• Biochemical Research: As a key intermediate for the chemical and enzymatic synthesis of complex sulfated glycans and glycosaminoglycans (GAGs) like heparin and heparan sulfate.
• Pharmaceutical Development: Used in the research and development of carbohydrate-based drugs, including anticoagulants, anti-inflammatory agents, and antiviral compounds.
• Enzyme Substrate & Inhibitor Studies: Serves as a specific substrate or inhibitor for sulfotransferases, glycosidases, and lectins to elucidate biological pathways.
• Diagnostic Reagent Production: Employed in the manufacture of diagnostic kits and tools for detecting and characterizing carbohydrate-binding proteins or specific disease markers.
• Glycobiology Tool: A fundamental tool for probing cell surface interactions, signal transduction, and other biological processes mediated by sulfated carbohydrates.
• Standards and Calibrants: Used as a high-purity reference standard in analytical laboratories for HPLC, MS, and NMR method development and quality control.

Basic Information

Product Name	Glcnac-3S,6S,2Na
CAS No.	157296-96-3
Molecular Formula	C8H12NNa2O12S2
Molecular Weight	439.33 g/mol
Synonyms	Disodium 3,6-di-O-sulfo-N-acetyl-D-glucosamine; N-Acetyl-D-glucosamine 3,6-disulfate disodium salt; 2-Acetamido-2-deoxy-D-glucopyranose 3,6-disulfate disodium salt; D-Glucosamine, N-acetyl-, 3,6-bis(hydrogen sulfate), disodium salt; GlcNAc-3S,6S disodium; 3,6-Di-O-sulfo-N-acetylglucosamine disodium salt; β-D-GlcpNAc-3S,6S disodium salt
EINECS	Contact for details

Quality Control

Our Glcnac-3S,6S,2Na is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by NMR and MS, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed batch-specific data are provided to guarantee traceability, consistency, and reliability for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive). Allow the container to reach room temperature before opening to minimize moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	< 20 ppm
Bacterial Endotoxins	< 1.0 EU/mg (if applicable)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.