Description

1-Azaspiro[4.4]Non-6-Ene-1-Carboxylicacid,8-Oxo-,1,1-Dimethylethylester is a high-value, advanced pharmaceutical intermediate characterized by its unique spirocyclic and lactam structure. This compound is essential for the synthesis of complex active pharmaceutical ingredients (APIs), particularly those targeting neurological and metabolic pathways. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of novel therapeutic agents and fine chemical synthesis.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex drug candidates, especially those with spirocyclic architectures.
• Neurological Drug Research: Used in the R&D of compounds targeting central nervous system (CNS) disorders.
• Protease Inhibitor Development: Serves as a precursor in the creation of enzyme inhibitors for therapeutic applications.
• Fine Chemical Synthesis: Employed in multi-step organic synthesis for constructing sophisticated molecular frameworks in academic and industrial labs.
• Chemical Biology Probes: Utilized in the development of molecular probes for studying biological mechanisms and target validation.

Basic Information

Product Name	1-Azaspiro[4.4]Non-6-Ene-1-Carboxylicacid,8-Oxo-,1,1-Dimethylethylester
CAS No.	157138-05-1
Molecular Formula	C13H19NO3
Molecular Weight	237.29 g/mol
Synonyms	tert-Butyl 8-oxo-1-azaspiro[4.4]non-6-ene-1-carboxylate; 1-Azaspiro[4.4]non-6-ene-1-carboxylic acid, 8-oxo-, 1,1-dimethylethyl ester; 1-Boc-8-oxo-1-azaspiro[4.4]non-6-ene; 8-Oxo-1-azaspiro[4.4]non-6-ene-1-carboxylic acid tert-butyl ester; tert-Butyl 8-oxo-1-azaspiro[4.4]non-6-ene-1-carboxylate; Boc-protected 8-oxo-1-azaspiro[4.4]non-6-ene
EINECS	Contact for details

Quality Control

Our 1-Azaspiro[4.4]Non-6-Ene-1-Carboxylicacid,8-Oxo-,1,1-Dimethylethylester is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high purity and structural integrity suitable for sensitive pharmaceutical applications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound is moisture-sensitive; keep the container tightly sealed under an inert atmosphere if necessary to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.