Description

6,7-Dimethyl-2,4-Di-1-Pyrrolidinyl-7H-Pyrrolo[2,3-D]Pyrimidine Hydrochloride is a high-purity, advanced pharmaceutical intermediate and research chemical. This compound is valued for its role as a key building block in the synthesis of complex heterocyclic molecules, particularly in medicinal chemistry. It is primarily sought by research institutions and pharmaceutical manufacturers engaged in the development of novel therapeutic agents, including kinase inhibitors and other targeted small-molecule drugs.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of targeted drug candidates, especially within oncology and anti-inflammatory research pipelines.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and the exploration of new chemical entities (NCEs) in drug discovery.
• Kinase Inhibitor Development: Used in the research and production of potential kinase inhibitors due to its pyrrolopyrimidine core structure, which is a privileged scaffold in this field.
• Biochemical Tool Compound: Employed in biochemical assays and as a reference standard to study specific biological pathways and enzyme interactions.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring high-purity, complex heterocycles.

Basic Information

Product Name	6,7-Dimethyl-2,4-Di-1-Pyrrolidinyl-7H-Pyrrolo[2,3-D]Pyrimidine Hydrochloride
CAS No.	157013-32-6
Molecular Formula	C18H26N6 • HCl
Molecular Weight	354.90 g/mol (Free base: 318.44 g/mol)
Synonyms	2,4-Bis(1-pyrrolidinyl)-6,7-dimethylpyrrolo[2,3-d]pyrimidine hydrochloride; 6,7-Dimethyl-2,4-di(pyrrolidin-1-yl)-7H-pyrrolo[2,3-d]pyrimidine hydrochloride; UNII-9V6H9I3V0C; 9V6H9I3V0C; Pyrrolo[2,3-d]pyrimidine, 6,7-dimethyl-2,4-di-1-pyrrolidinyl-, hydrochloride (1:1); 6,7-Dimethyl-2,4-di-1-pyrrolidinyl-7H-pyrrolo[2,3-d]pyrimidine monohydrochloride
EINECS	Contact for details

Quality Control

Our 6,7-Dimethyl-2,4-Di-1-Pyrrolidinyl-7H-Pyrrolo[2,3-D]Pyrimidine Hydrochloride is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the stringent requirements for pharmaceutical research and development. A detailed Certificate of Analysis (COA) documenting purity, assay, and impurity profiles is provided with each shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%; Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.