Description

1,7-Dibenzyl-1,4,7,10-Tetraazacyclododecane is a functionalized macrocyclic tetraamine ligand, a key intermediate in the synthesis of sophisticated chelating agents and catalysts. This compound matters for its ability to form stable, well-defined complexes with a variety of metal ions, enabling precise control in chemical processes. It is primarily needed by researchers and manufacturers in the fields of magnetic resonance imaging (MRI) contrast agents, radiopharmaceuticals, catalysis, and advanced materials science.

Application

• MRI Contrast Agent Precursor: A critical building block for synthesizing gadolinium(III) and other lanthanide-based contrast agents used in medical diagnostics.
• Radiopharmaceutical Chelator: Used to develop bifunctional chelators for labeling antibodies, peptides, and other targeting molecules with radioisotopes (e.g., 64Cu, 68Ga) for PET imaging and targeted radiotherapy.
• Homogeneous Catalysis: Serves as a ligand scaffold for transition metal catalysts in organic synthesis, including oxidation and coupling reactions.
• Chemical Sensing & Separation: Incorporated into sensors and separation materials for the selective binding and detection of specific metal ions.
• Materials Science: Used in the development of metal-organic frameworks (MOFs), single-molecule magnets, and other functional materials.
• Academic & Industrial Research: A valuable reagent for exploring new coordination chemistry, developing novel chelating systems, and prototyping new applications.

Basic Information

Product Name	1,7-Dibenzyl-1,4,7,10-Tetraazacyclododecane
CAS No.	156970-79-5
Molecular Formula	C26H40N4
Molecular Weight	408.63 g/mol
Synonyms	1,7-Dibenzyl-1,4,7,10-tetraazacyclododecane; 1,4,7,10-Tetraazacyclododecane, 1,7-dibenzyl-; 1,7-Dibenzyl-cyclen; 1,7-Dibenzyl-tetraazacyclododecane; 1,7-DBn-cyclen; Dibenzyldodecane; 1,7-Bis(benzyl)-1,4,7,10-tetraazacyclododecane
EINECS	Contact for details

Quality Control

Our 1,7-Dibenzyl-1,4,7,10-Tetraazacyclododecane is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity, essential for sensitive applications like pharmaceutical intermediate synthesis. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing purity, identity, and impurity profiles. Our quality systems are designed to support cGMP and ISO standards for traceability and documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents. For long-term storage, consider an inert atmosphere to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.