Description

2-Bromo-2,3-Dihydro-4-Fluoro-1H-Inden-1-One is a high-value, halogenated indanone derivative serving as a critical synthetic intermediate in advanced organic chemistry. This compound matters for its role in constructing complex molecular architectures, particularly in the development of novel active pharmaceutical ingredients (APIs) and functional materials. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce specific bromo and fluoro substituents into target molecules.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of potential drug candidates, especially in medicinal chemistry programs targeting central nervous system (CNS) disorders or inflammatory diseases.
• Agrochemical Research: Used in the development of new herbicides, fungicides, or insecticides where the bromo-fluoro-indanone scaffold may confer specific biological activity.
• Material Science Precursor: Serves as a monomer or functionalizing agent in the synthesis of advanced polymers, liquid crystals, or organic electronic materials.
• Chemical Biology Probe Synthesis: Employed to create tagged or modified chemical probes for studying enzyme mechanisms or protein-ligand interactions.
• Cross-Coupling Reactions: The bromine atom makes it a suitable substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck) to form carbon-carbon bonds.
• Fluorine Chemistry Studies: Used as a model compound in research exploring the effects of fluorine substitution on chemical reactivity and physical properties.

Basic Information

Product Name	2-Bromo-2,3-Dihydro-4-Fluoro-1H-Inden-1-One
CAS No.	156484-68-3
Molecular Formula	C9H6BrFO
Molecular Weight	229.05 g/mol
Synonyms	2-Bromo-4-fluoroindan-1-one; 4-Fluoro-2-bromoindan-1-one; 1H-Inden-1-one, 2-bromo-2,3-dihydro-4-fluoro-; 2-Bromo-4-fluoro-2,3-dihydro-1H-inden-1-one; 156484-68-3; 2-Bromo-4-fluoroindanone
EINECS	Contact for details

Quality Control

Every batch of 2-Bromo-2,3-Dihydro-4-Fluoro-1H-Inden-1-One is produced and tested under a strict quality management system. We ensure compliance with relevant industry standards for fine chemical intermediates. A comprehensive Certificate of Analysis (COA) is provided with each shipment, detailing purity, identity, and impurity profiles as determined by advanced analytical techniques. Our quality commitment ensures material consistency and traceability for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from strong acids and incompatible organic solvents. The container should be kept tightly sealed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.