Description

Oxiranepropanol, 3-Ethynyl-, trans- (9Ci) is a specialized, high-value oxirane derivative featuring both an epoxide ring and an ethynyl (acetylene) functional group, making it a versatile building block for advanced organic synthesis. This unique bifunctional structure is critical for introducing reactive handles and constructing complex molecular architectures, such as polymers, dendrimers, and pharmaceutical intermediates. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for applications in click chemistry, cross-coupling reactions, and polymer modification.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for introducing alkyne tags for bioconjugation or creating novel heterocyclic scaffolds.
• Agrochemical Synthesis: Used in the development of new herbicides, fungicides, and plant growth regulators where the epoxide and alkyne groups enable unique modes of action.
• Polymer & Material Science: Acts as a monomer or cross-linking agent for producing specialty polymers, epoxy resins, and functionalized surfaces with tailored properties.
• Click Chemistry Reagent: The terminal alkyne group makes it an ideal participant in copper-catalyzed azide-alkyne cycloaddition (CuAAC) reactions for labeling, bioconjugation, and material surface modification.
• Ligand & Catalyst Development: Employed in the synthesis of novel ligands and organometallic catalysts for asymmetric synthesis and other catalytic processes.
• Research & Development: A valuable tool in academic and industrial R&D for exploring new synthetic methodologies and creating compound libraries for screening.

Basic Information

Product Name	Oxiranepropanol, 3-Ethynyl-, trans- (9Ci)
CAS No.	156455-52-6
Molecular Formula	C5H6O2
Molecular Weight	98.10 g/mol
Synonyms	trans-3-Ethynyloxiranemethanol; 3-Ethynyloxiran-2-ylmethanol; 2-(Oxiran-2-yl)ethynylmethanol; Glycidyl ethynyl carbinol; 3-Ethynylglycidol; Oxiranemethanol, 3-ethynyl-, trans-; Propargyl glycidyl ether alcohol derivative; (2R,3S)-3-Ethynyloxiran-2-ylmethanol (enantiomer)
EINECS	Contact for details

Quality Control

Every batch of Oxiranepropanol, 3-Ethynyl-, trans- (9Ci) is produced and tested under strict quality management protocols. We employ advanced analytical techniques including GC, HPLC, and NMR to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing assay, impurity profile, and physical properties is provided with each shipment. Our quality system is designed to meet the stringent requirements of cGMP and ISO standards for fine chemical manufacturing.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at temperatures between 2°C and 8°C (refrigerated) to maximize stability, given its hygroscopic and light-sensitive nature. Keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent moisture absorption and potential decomposition. Isolate from incompatible materials such as strong acids, bases, and oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 97.0%
Purity (HPLC)	≥ 96.0%
Water Content (KF)	≤ 0.5%
Specific Rotation (if chiral)	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.