Description

2-Amino-1-Methylimidazo[4,5-B]Quinoline is a heterocyclic aromatic amine of significant interest in biochemical and toxicological research. This compound matters as a key reference standard and synthetic intermediate for studying mutagenic and carcinogenic processes related to cooked food products. It is primarily needed by research institutions, analytical laboratories, and pharmaceutical developers focused on metabolic activation studies, DNA adduct formation, and the development of detection methodologies.

Application

• Biochemical Research Standard: Serves as a certified reference material (CRM) for calibrating analytical instruments in studies of heterocyclic aromatic amines (HAAs).
• Toxicology & Mutagenicity Studies: Used as a model compound to investigate the metabolic pathways, genotoxicity, and carcinogenic potential of amine derivatives formed during high-temperature cooking.
• Analytical Method Development: Essential for developing and validating sensitive detection methods, such as LC-MS/MS or GC-MS, for trace analysis of food-borne contaminants.
• Pharmaceutical Intermediate: Acts as a specialized building block in the synthesis of more complex molecules for pharmacological screening.
• Food Safety & Quality Control: Employed by testing laboratories to monitor and quantify the presence of potentially harmful amines in processed foodstuffs.
• Academic Research: Utilized in university and institutional labs for fundamental research on DNA damage and repair mechanisms.

Basic Information

Product Name	2-Amino-1-Methylimidazo[4,5-B]Quinoline
CAS No.	156215-58-6
Molecular Formula	C11H10N4
Molecular Weight	198.23 g/mol
Synonyms	1-Methyl-2-aminoimidazo[4,5-b]quinoline; 2-Amino-1-methylimidazo[4,5-b]quinoline; 2-Amino-1-MIQ; IQx; 1-Methyl-IQ; Imidazo[4,5-b]quinolin-2-amine, 1-methyl-; 1-Methyl-2-aminoimidazoquinoline
EINECS	Contact for details

Quality Control

Our 2-Amino-1-Methylimidazo[4,5-B]Quinoline is produced and handled under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity verification and spectroscopic methods for structural confirmation, to ensure it meets the high standards required for research applications. Certificates of Analysis (COA) with detailed chromatographic data are available upon request to support your regulatory and quality assurance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	Off-white to light brown powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Loss on Drying	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.