Description

1-Indolizinol, Octahydro-6,7,8-Tris(Methoxymethoxy)-, 1R-(1.Alpha.,6.Alpha.,7.Beta.,8.Alpha.,8A.Alpha.)- is a complex, stereochemically defined indolizidine alkaloid derivative, serving as a critical advanced pharmaceutical intermediate for the synthesis of bioactive molecules. Its precise stereochemistry and functionalization make it a valuable scaffold for medicinal chemistry research and the development of new therapeutic agents. This high-purity compound is primarily utilized by pharmaceutical R&D and fine chemical synthesis teams focused on creating novel drug candidates.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of complex natural product analogs and potential drug candidates targeting neurological and infectious diseases.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• Asymmetric Synthesis: Serves as a chiral template or starting material for the preparation of enantiomerically pure compounds.
• Alkaloid Chemistry: Fundamental reagent for the study and synthesis of indolizidine and related polycyclic alkaloid families.
• Process Chemistry Development: Employed in the scale-up and optimization of synthetic routes for active pharmaceutical ingredients (APIs).
• Academic & Institutional Research: Used in universities and research institutes for investigations into novel synthetic methodologies and biological activity.

Basic Information

Product Name	1-Indolizinol, Octahydro-6,7,8-Tris(Methoxymethoxy)-, 1R-(1.Alpha.,6.Alpha.,7.Beta.,8.Alpha.,8A.Alpha.)-
CAS No.	156150-88-8
Molecular Formula	C15H29NO6
Molecular Weight	319.40 g/mol
Synonyms	(1R,6R,7S,8R,8aR)-Octahydro-6,7,8-tris(methoxymethoxy)indolizin-1-ol; 1-Indolizinol, octahydro-6,7,8-tris(methoxymethoxy)-, (1R,6R,7S,8R,8aR)-; (1R,6R,7S,8R,8aR)-1-Hydroxyoctahydro-6,7,8-tris(methoxymethoxy)indolizine; Indolizidine alkaloid derivative MOM-protected; 1R,6R,7S,8R,8aR-Isomer of Octahydro-6,7,8-tris(methoxymethoxy)indolizin-1-ol
EINECS	Contact for details

Quality Control

Our 1-Indolizinol, Octahydro-6,7,8-Tris(Methoxymethoxy)-, 1R-(1.Alpha.,6.Alpha.,7.Beta.,8.Alpha.,8A.Alpha.)- is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure high chemical purity and stereochemical integrity, meeting the stringent requirements of pharmaceutical R&D. Certificates of Analysis (COA) detailing identity, purity (HPLC), chiral purity, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); ensure the container is sealed under an inert atmosphere after each use to prevent degradation. Keep away from strong acids and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.