Description

Tetrabutylammonium (6-Iodo-1H-Purin-2-Yl)Amide is a high-purity, organoammonium salt derivative of a modified purine nucleobase, serving as a critical synthetic intermediate and reagent. This compound matters for its role in facilitating advanced organic synthesis, particularly in the construction of complex heterocyclic systems and nucleoside analogs. Pharmaceutical researchers, agrochemical developers, and specialty chemical manufacturers need it for applications in drug discovery, material science, and the development of novel bioactive molecules.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel purine-based drug candidates, including kinase inhibitors and antiviral agents.
• Nucleoside & Nucleotide Chemistry: Used in the modification and functionalization of nucleosides for medicinal chemistry and biochemical research.
• Agrochemical Research: Serves as a precursor in developing new plant growth regulators or herbicides with specific mode-of-action targets.
• Material Science: Potential monomer or additive in the creation of specialty polymers and advanced organic electronic materials.
• Cross-Coupling Reactions: The iodine substituent makes it a valuable substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Sonogashira) to create diverse chemical libraries.
• Bioconjugation & Probe Development: Useful for labeling biomolecules or creating fluorescent or affinity probes for diagnostic and research applications.

Basic Information

Product Name	Tetrabutylammonium (6-Iodo-1H-Purin-2-Yl)Amide
CAS No.	156126-48-6
Molecular Formula	C₂₁H₃₇IN₆
Molecular Weight	524.47 g/mol
Synonyms	6-Iodo-2-(tetrabutylammonio)aminopurine; Tetrabutylammonium 6-iodo-1H-purin-2-ylamide; 6-Iodopurine-2-ylamide tetrabutylammonium salt; N-(6-Iodo-1H-purin-2-yl)-N,N,N-tributylbutan-1-aminium; 2-Amino-6-iodopurine tetrabutylammonium salt; TBAA-6IP; (6-Iodo-1H-purin-2-yl)amide tetrabutylammonium derivative
EINECS	Contact for details

Quality Control

Our Tetrabutylammonium (6-Iodo-1H-Purin-2-Yl)Amide is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and heavy metals to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) documenting all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container should be kept in a desiccated environment. For long-term storage, consider using an inert atmosphere to ensure optimal stability.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.