Description

Diendo-3-(4-Methyl-Benzoyl)-Bicyclo[2.2.1]Heptane-2-Carboxylic Acid is a specialized bicyclic organic compound featuring a carboxylic acid group and a 4-methylbenzoyl moiety. This unique molecular architecture makes it a valuable advanced pharmaceutical intermediate (API intermediate) and a versatile building block in sophisticated organic synthesis. It is primarily sought after by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers for the development of novel active ingredients and complex molecular structures.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and production of proprietary drug candidates, particularly those targeting central nervous system (CNS) disorders or acting as enzyme inhibitors.
• Asymmetric Synthesis: Utilized as a precursor or chiral auxiliary in stereoselective reactions to construct complex molecules with high enantiomeric purity.
• Ligand and Catalyst Development: Serves as a foundational structure for creating novel ligands used in catalytic systems for organic transformations.
• Material Science Research: Investigated as a monomer or additive for synthesizing specialized polymers with tailored thermal or optical properties.
• Agrochemical Intermediate: Potential use in the synthesis of advanced, high-efficacy crop protection agents.
• Academic & Industrial R&D: Employed in methodological studies and discovery chemistry for new reaction pathways.

Basic Information

Item	Details
Product Name	Diendo-3-(4-Methyl-Benzoyl)-Bicyclo[2.2.1]Heptane-2-Carboxylic Acid
CAS No.	155955-96-7
Molecular Formula	C16H18O3
Molecular Weight	258.31 g/mol
Synonyms	3-(4-Methylbenzoyl)bicyclo[2.2.1]heptane-2-carboxylic acid; endo-3-(4-Methylbenzoyl)-2-norbornanecarboxylic acid; Bicyclo[2.2.1]heptane-2-carboxylic acid, 3-(4-methylbenzoyl)-, endo-; Diendo-3-(p-Toluoyl)-2-norbornanecarboxylic Acid; Diendo-NBCOOH-Toluoyl; 155955-96-7; (1R,2S,3R,4S)-3-(4-Methylbenzoyl)bicyclo[2.2.1]heptane-2-carboxylic acid (stereoisomer)
EINECS	Contact for details

Quality Control

Our production of Diendo-3-(4-Methyl-Benzoyl)-Bicyclo[2.2.1]Heptane-2-Carboxylic Acid adheres to a stringent quality management system. Every batch undergoes comprehensive analytical testing, including HPLC for purity and chiral purity, NMR, and MS for structural confirmation, to ensure it meets exacting customer specifications. We provide a detailed Certificate of Analysis (COA) with each shipment, guaranteeing traceability and compliance with relevant cGMP and ISO 9001 standards for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from strong acids and organic solvents. For long-term storage, consider inert atmosphere conditions to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee (Diendo isomer)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.