Description

Threo-1-(4-Hydroxyphenyl)Propane-1,2,3-Triol is a specialized organic compound belonging to the class of phenolic polyols. This high-purity chemical building block is valued for its unique stereochemistry and functional groups, which make it a critical intermediate in advanced synthetic pathways. It is primarily sought by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and fine chemical sectors for developing novel active ingredients and complex molecules. The compound is supplied under stringent quality control to ensure batch-to-batch consistency for sensitive applications.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the research and development of new drug candidates, particularly for central nervous system (CNS) and metabolic disorder therapeutics.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and plant growth regulators where specific stereochemistry influences biological activity.
• Fine Chemical Manufacturing: Acts as a precursor for synthesizing complex ligands, catalysts, and specialty polymers requiring precise molecular architecture.
• Biochemical Research: Employed in enzymatic studies and as a standard for analytical method development due to its defined stereoisomeric form.
• Material Science: Investigated for use in epoxy resin formulations and other high-performance polymeric materials where the phenolic and hydroxyl groups contribute to cross-linking.

Basic Information

Product Name	Threo-1-(4-Hydroxyphenyl)Propane-1,2,3-Triol
CAS No.	155748-73-5
Molecular Formula	C9H12O4
Molecular Weight	184.19 g/mol
Synonyms	Threo-1-(4-Hydroxyphenyl)glycerol; (1R,2S)-1-(4-Hydroxyphenyl)propane-1,2,3-triol; (1S,2R)-1-(4-Hydroxyphenyl)propane-1,2,3-triol; 4-Hydroxyphenylglycerol (threo-); 1,2,3-Propanetriol, 1-(4-hydroxyphenyl)-, (1R,2S)-rel-; Threo-Phenylglycerol Derivative; HPG (threo isomer); Contact for additional trade names.
EINECS	Contact for details

Quality Control

Every batch of Threo-1-(4-Hydroxyphenyl)Propane-1,2,3-Triol is manufactured and analyzed under a strict quality management system. We provide comprehensive analytical documentation, including a Certificate of Analysis (COA) detailing purity, chiral purity, and impurity profiles. Our quality protocols are designed to meet the exacting standards of pharmaceutical and research applications, ensuring identity, strength, and composition. Certificates are available upon request and can support regulatory filings.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The product is light-sensitive (store away from light). Keep the container tightly sealed to protect from moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% (Threo isomer)
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.