Description

6,9-Diazaspiro[4.5]Decane-7,10-Dione,8-Methyl-,(R)-(9Ci) is a high-purity chiral spirocyclic compound, a key structural motif and advanced pharmaceutical intermediate. Its defined stereochemistry and rigid spiro-fused ring system make it a valuable building block for the synthesis of complex bioactive molecules. This compound is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel therapeutics, particularly in medicinal chemistry and process R&D.

Application

• Pharmaceutical Intermediate: Serves as a critical chiral synthon in the multi-step synthesis of active pharmaceutical ingredients (APIs), especially for central nervous system (CNS) and antiviral drug candidates.
• Medicinal Chemistry Research: Used as a constrained scaffold for constructing compound libraries in structure-activity relationship (SAR) studies and high-throughput screening (HTS).
• Asymmetric Synthesis: Employed as a starting material or chiral auxiliary in catalytic asymmetric reactions to induce stereoselectivity.
• Ligand and Catalyst Development: Its nitrogen-containing heterocyclic structure is valuable for designing novel chelating ligands and organocatalysts.
• Chemical Biology Probes: Utilized in the development of molecular probes to study enzyme function and biological pathways due to its specific three-dimensional geometry.

Basic Information

Product Name	6,9-Diazaspiro[4.5]Decane-7,10-Dione,8-Methyl-,(R)-(9Ci)
CAS No.	155689-63-7
Molecular Formula	C9H14N2O2
Molecular Weight	182.22 g/mol
Synonyms	(R)-8-Methyl-6,9-diazaspiro[4.5]decane-7,10-dione; (8R)-8-Methyl-6,9-diazaspiro[4.5]decane-7,10-dione; 8-Methyl-6,9-diazaspiro[4.5]decane-7,10-dione, (R)-; (R)-8-Methyl-1,4-diazaspiro[4.5]decane-2,3-dione; (R)-8-Methyl-1,4-diazaspiro[4.5]decane-2,3-dione; 155689-63-7; (R)-8-Methyl-6,9-diazaspiro[4.5]decane-7,10-dione
EINECS	Contact for details

Quality Control

Our 6,9-Diazaspiro[4.5]Decane-7,10-Dione,8-Methyl-,(R)-(9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification, to ensure it meets the high standards required for pharmaceutical research and development. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which may affect stability and performance.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.