Description

S-(4,5-Dimethoxy-2-Nitrobenzyl)Isothiouronium Bromide is a specialized organic bromide salt with a protected nitrobenzyl group, serving as a key synthetic intermediate and photolabile protecting group precursor. This compound matters for its role in advanced organic synthesis, particularly in the development of light-sensitive compounds and caged molecules for biological research. It is primarily needed by pharmaceutical R&D teams, fine chemical manufacturers, and academic research laboratories focused on photochemistry, prodrug design, and controlled-release systems.

Application

• As a photolabile protecting group precursor for carboxylic acids, phosphates, and amines in peptide and nucleotide synthesis.
• Critical synthetic intermediate in the preparation of caged neurotransmitters and signaling molecules for physiological studies.
• Used in the research and development of prodrugs and targeted drug delivery systems activated by light.
• Employed in material science for creating light-responsive polymers and surfaces.
• As a reagent in organic methodology development for novel coupling and deprotection reactions.
• Serves as a building block for advanced chromophores and photoactive dyes.

Basic Information

Product Name	S-(4,5-Dimethoxy-2-Nitrobenzyl)Isothiouronium Bromide
CAS No.	155614-05-4
Molecular Formula	C₁₀H₁₄BrN₃O₄S
Molecular Weight	352.21 g/mol
Synonyms	S-(4,5-Dimethoxy-2-nitrobenzyl)isothiouronium bromide; 2-[(4,5-Dimethoxy-2-nitrobenzyl)thio]-2-thiopseudourea hydrobromide; 4,5-Dimethoxy-2-nitrobenzyl isothiouronium bromide; Isothiouronium, S-(4,5-dimethoxy-2-nitrobenzyl)-, bromide; DNIB-ITU Br; (4,5-Dimethoxy-2-nitrobenzyl)thiourea hydrobromide (common name variant); Contact for additional trade names.
EINECS	Contact for details

Quality Control

Our S-(4,5-Dimethoxy-2-Nitrobenzyl)Isothiouronium Bromide is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR for structural confirmation, and KF titration for moisture content, to ensure it meets the high standards required for research and synthesis. Certificates of Analysis (COA) with full traceability are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.