Description

3-[(tert-Butoxycarbonyl-Methyl-Amino)-Methyl]-Benzoic Acid is a high-purity, protected amino acid derivative widely used as a critical building block in advanced organic synthesis. This compound is valued for its role in introducing a functionalized benzoic acid moiety with a protected amine group, enabling precise molecular construction. It is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries developing novel active ingredients and complex organic molecules.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds requiring a functionalized aromatic carboxylic acid with a protected amine handle.
• Peptidomimetics & Drug Discovery: Used in medicinal chemistry for constructing peptide analogs and non-peptide scaffolds that mimic bioactive peptides.
• Agrochemical Synthesis: Serves as a building block for developing novel herbicides, fungicides, and plant growth regulators with specific aromatic acid functionalities.
• Ligand & Catalyst Development: Employed in the preparation of specialized ligands for metal catalysis and organocatalysts used in asymmetric synthesis.
• Polymer & Material Science: Acts as a monomer or functionalization agent for creating specialty polymers with tailored properties, such as polyamides or functional coatings.
• Bioconjugation & Linker Chemistry: Utilized in the design of cleavable linkers and spacer arms for bioconjugation applications in diagnostics and targeted therapies.

Basic Information

Product Name	3-[(tert-Butoxycarbonyl-Methyl-Amino)-Methyl]-Benzoic Acid
CAS No.	155567-87-6
Molecular Formula	C15H21NO4
Molecular Weight	279.33 g/mol
Synonyms	3-[(N-Boc-N-methylamino)methyl]benzoic acid; 3-((((tert-Butoxy)carbonyl)(methyl)amino)methyl)benzoic acid; N-Boc-N-methyl-3-aminomethylbenzoic acid; 3-[(tert-Butoxycarbonyl)(methyl)aminomethyl]benzoic Acid; 3-[(N-Boc-N-methyl)aminomethyl]benzoic acid; Benzoic acid, 3-[[[(1,1-dimethylethoxy)carbonyl]methylamino]methyl]-; 3-((tert-Butoxycarbonyl(methyl)amino)methyl)benzoic acid
EINECS	Contact for details

Quality Control

Our 3-[(tert-Butoxycarbonyl-Methyl-Amino)-Methyl]-Benzoic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high chemical purity and structural integrity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.