Description

4-(Trifluoromethyl)Quinoline-3-Carboxylic Acid is a high-value, multi-functional heterocyclic building block characterized by its quinoline core and trifluoromethyl group. This compound is essential for advanced organic synthesis, offering a unique combination of structural rigidity and fluorine-derived electronic properties that are critical for modulating the bioactivity and physicochemical characteristics of target molecules. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the creation of novel active ingredients and specialty materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly for kinase inhibitors, anti-infectives, and central nervous system (CNS) agents.
• Agrochemical Research: Used to develop new herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances lipophilicity and metabolic stability.
• Material Science: Serves as a building block for advanced organic electronic materials, such as ligands for metal-organic frameworks (MOFs) or components in organic light-emitting diodes (OLEDs).
• Chemical Biology Probe Development: Employed in the design and synthesis of molecular probes and fluorescent tags for studying biological processes.
• Academic & Industrial R&D: A versatile scaffold for method development in organic chemistry and for exploring new chemical spaces in discovery libraries.

Basic Information

Product Name	4-(Trifluoromethyl)Quinoline-3-Carboxylic Acid
CAS No.	155495-82-2
Molecular Formula	C11H6F3NO2
Molecular Weight	241.17 g/mol
Synonyms	3-Quinolinecarboxylic acid, 4-(trifluoromethyl)-; 4-(Trifluoromethyl)-3-quinolinecarboxylic acid; 4-Trifluoromethylquinoline-3-carboxylic acid; Quinoline-3-carboxylic acid, 4-(trifluoromethyl)-; 155495-82-2; 4-(Trifluoromethyl)quinoline-3-carboxylic acid
EINECS	Contact for details

Quality Control

Our production of 4-(Trifluoromethyl)Quinoline-3-Carboxylic Acid adheres to stringent quality management protocols. Each batch is subjected to comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and moisture content. We provide a detailed Certificate of Analysis (COA) with every shipment to ensure full traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.