Description

Methyl(2E)-[2-(Chloromethyl)Phenyl](Methoxyimino)Acetate CAS NO 155380-13-5 is a high-purity, advanced pharmaceutical intermediate characterized by its specific oxime ester structure. This compound is critical for ensuring the precise synthesis and consistent quality of active pharmaceutical ingredients (APIs) in final drug formulations. It is primarily required by R&D laboratories and manufacturing facilities in the pharmaceutical and agrochemical sectors for the development and production of novel therapeutic agents and crop protection products.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex APIs, particularly for anti-inflammatory, antimicrobial, or central nervous system (CNS) agents.
• Agrochemical Synthesis: Used in the production pathway for modern fungicides or insecticides, contributing to effective crop protection solutions.
• Chemical Research & Development: Serves as a versatile synthon in organic chemistry for constructing molecules with methoxyimino and chloromethyl functional groups.
• Process Chemistry & Scale-Up: Employed in pilot plants and commercial manufacturing for process optimization and the production of target compounds at scale.
• Fine Chemical Production: Integral to the manufacture of other specialty fine chemicals and custom synthesis projects requiring high-purity intermediates.

Basic Information

Product Name	Methyl(2E)-[2-(Chloromethyl)Phenyl](Methoxyimino)Acetate
CAS No.	155380-13-5
Molecular Formula	C12H14ClNO3
Molecular Weight	255.70 g/mol
Synonyms	Methyl (2E)-2-[2-(Chloromethyl)phenyl]-2-(methoxyimino)acetate; (2E)-2-[2-(Chloromethyl)phenyl]-2-(methoxyimino)acetic acid methyl ester; Methyl α-[2-(chloromethyl)phenyl]-α-(methoxyimino)acetate; Methyl O-methyl-2-[2-(chloromethyl)phenyl]glyoxylate oxime; 155380-13-5; Methyl 2-(2-chloromethylphenyl)-2-(methoxyimino)acetate
EINECS	Contact for details

Quality Control

Our Methyl(2E)-[2-(Chloromethyl)Phenyl](Methoxyimino)Acetate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure it meets stringent purity and identity specifications. A comprehensive Certificate of Analysis (COA) documenting all test results is provided with each shipment to guarantee traceability and compliance with your quality standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from strong oxidizing agents, strong acids, and strong bases. The container must be kept tightly sealed due to the compound's sensitivity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.5%
Related Substances (HPLC)	Total impurities ≤ 1.5% Any single impurity ≤ 0.5%
Residual Solvents (GC)	Complies with ICH guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.