Description

Fmoc-3-Aminomethylbenzoic Acid is a high-purity, protected amino acid derivative essential for solid-phase peptide synthesis (SPPS). This compound serves as a critical building block, enabling the controlled incorporation of a meta-substituted benzylamine moiety into complex peptide sequences. It is primarily utilized by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers developing novel therapeutic peptides, diagnostic agents, and biochemical tools.

Application

• Solid-Phase Peptide Synthesis (SPPS): A key Fmoc-protected intermediate for the sequential assembly of custom peptides.
• Pharmaceutical Research: Synthesis of peptide-based drug candidates, including hormone analogs and enzyme inhibitors.
• Bioconjugation: Creating peptide tags, linkers, or probes for antibody-drug conjugates (ADCs) and diagnostic imaging agents.
• Combinatorial Chemistry: Used in libraries for high-throughput screening to discover new bioactive molecules.
• Material Science: Incorporation into specialized polymers or surface coatings with specific bio-functional properties.
• Academic Research: Fundamental studies in organic chemistry, biochemistry, and medicinal chemistry.

Basic Information

Product Name	Fmoc-3-Aminomethylbenzoic Acid
CAS No.	155369-11-2
Molecular Formula	C23H19NO4
Molecular Weight	373.40 g/mol
Synonyms	Fmoc-3-(Aminomethyl)benzoic Acid; 3-[(9H-Fluoren-9-ylmethoxycarbonyl)aminomethyl]benzoic Acid; N-Fmoc-3-aminomethylbenzoic Acid; N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-3-(aminomethyl)benzoic Acid; Fmoc-AMB-OH; Fmoc-3-Amba; Fmoc-meta-aminomethylbenzoic Acid
EINECS	Contact for details

Quality Control

Our Fmoc-3-Aminomethylbenzoic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR for structural confirmation, and chiral analysis where applicable, to ensure it meets the stringent requirements for peptide synthesis. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C (refrigerated) or as specified on the label. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Assay (HPLC)	≥98.0%
Water Content (KF)	≤0.5%
Heavy Metals	≤20 ppm
Residual Solvents (GC)	Meets ICH guidelines
Optical Purity (Chiral HPLC)	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.