Description

[2-(2-Nitro-Phenyl)-2-Oxo-Ethyl]-Carbamic Acid tert-Butyl Ester is a specialized organic intermediate featuring a nitro-substituted aromatic ring and a protected carbamate functional group. This compound matters for its role as a versatile building block in the synthesis of more complex molecules, particularly in pharmaceutical research and development. It is primarily needed by fine chemical manufacturers and R&D laboratories engaged in the creation of active pharmaceutical ingredients (APIs) and other nitrogen-containing heterocycles.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of novel drug candidates, especially those targeting neurological or oncological pathways.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging its nitro-aromatic structure.
• Peptide Chemistry: Serves as a protected amine synthon for the controlled introduction of amino acid derivatives in peptide coupling reactions.
• Material Science: Potential monomer or cross-linking agent in the development of specialty polymers with specific optical or electronic properties.
• Academic & Contract Research: Employed in university and CRO settings for methodological studies in organic synthesis and catalysis.

Basic Information

Product Name	[2-(2-Nitro-Phenyl)-2-Oxo-Ethyl]-Carbamic Acid tert-Butyl Ester
CAS No.	155301-81-8
Molecular Formula	C₁₃H₁₆N₂O₅
Molecular Weight	280.28 g/mol
Synonyms	tert-Butyl N-[2-(2-nitrophenyl)-2-oxoethyl]carbamate; 2-[(tert-Butoxycarbonyl)amino]-1-(2-nitrophenyl)ethan-1-one; BOC-2-Amino-2'-nitroacetophenone; N-BOC-2-Amino-2'-nitroacetophenone; (2-Nitrobenzoyl)methyl Carbamic Acid tert-Butyl Ester; 1-(2-Nitrophenyl)-2-[(tert-butoxycarbonyl)amino]ethanone; 155301-81-8
EINECS	Contact for details

Quality Control

Our production of [2-(2-Nitro-Phenyl)-2-Oxo-Ethyl]-Carbamic Acid tert-Butyl Ester adheres to stringent in-process controls to ensure batch-to-batch consistency and high purity. Every lot is fully characterized and undergoes rigorous analytical testing. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided and available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, handling and packaging should minimize exposure to direct light.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.