Description

2'-Azidoethyl A-Mannopyranoside is a specialized synthetic glycoside derivative, featuring an azidoethyl spacer group attached to the anomeric carbon of mannose. This compound is a crucial intermediate in the synthesis of complex glycoconjugates and glycoclusters, enabling advanced research in glycobiology and medicinal chemistry. It is primarily utilized by researchers and manufacturers in the pharmaceutical, biotechnology, and diagnostic sectors for developing novel therapeutics, vaccines, and targeted delivery systems.

Application

• Glycoconjugate Synthesis: A key building block for creating neoglycoproteins, glycolipids, and glycopolymers via click chemistry (e.g., CuAAC with alkynes).
• Drug Discovery & Development: Used in the design and synthesis of carbohydrate-based drug candidates, prodrugs, and targeted delivery vehicles.
• Diagnostic Reagent Production: Serves as a precursor for manufacturing labeled probes and biosensors for detecting specific carbohydrate-binding proteins (lectins).
• Biomaterial Functionalization: Employed to introduce mannose residues onto surfaces, nanoparticles, or polymers to study cell-surface interactions or create bioactive materials.
• Chemical Biology Tools: Essential for probing carbohydrate-mediated biological processes, such as cell signaling, immune response, and pathogen recognition.
• Vaccine Adjuvant Research: Investigated for its potential in constructing synthetic carbohydrate antigens to elicit specific immune responses.

Basic Information

Product Name	2'-Azidoethyl A-Mannopyranoside
CAS No.	155196-97-7
Molecular Formula	C8H15N3O6
Molecular Weight	249.22 g/mol
Synonyms	2'-Azidoethyl α-D-Mannopyranoside; α-D-Mannopyranoside, 2-azidoethyl; Azidoethyl α-Mannoside; 2-Azidoethyl α-D-Mannopyranoside; 2-Azidoethyl α-Mannoside; 2'-Azidoethyl α-Mannoside; 1-O-(2-Azidoethyl)-α-D-mannopyranoside; Mannose azidoethyl glycoside
EINECS	Contact for details

Quality Control

Our 2'-Azidoethyl A-Mannopyranoside is manufactured under controlled conditions to ensure high purity and batch-to-batch consistency. Each lot undergoes rigorous analytical testing, including HPLC for purity assessment and NMR for structural confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our quality management system supports compliance with cGMP guidelines for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability. For long-term storage, consider storing under an inert atmosphere in a freezer (-20°C). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.