Description

2-Cyclobuten-1-Ol, 1-Ethynyl-4-Methoxy-4-Methyl-, cis- (9Ci) is a specialized, high-value organic building block featuring a unique cis-configured cyclobutene alcohol core functionalized with ethynyl and methoxy-methyl groups. This compound is of significant interest in advanced organic synthesis and pharmaceutical research due to its strained ring system and multiple reactive sites, enabling the construction of complex molecular architectures. It serves as a critical precursor for medicinal chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors seeking to develop novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of novel drug candidates, particularly in developing targeted therapies and enzyme inhibitors.
• Agrochemical Research: Used in the design and synthesis of new generation herbicides, fungicides, and plant growth regulators with enhanced efficacy.
• Advanced Material Synthesis: Serves as a monomer or cross-linking agent in the development of specialty polymers, liquid crystals, and photoactive materials.
• Organic Synthesis Building Block: Utilized in [3+2] and [2+2] cycloaddition reactions, ring-opening polymerizations, and other transformations to create complex, strained carbocycles.
• Academic & R&D Laboratories: Employed in methodological studies and as a reference standard for stereoselective synthesis research.
• Fine Chemical Production: Acts as a precursor for flavors, fragrances, and other high-value specialty chemicals requiring specific stereochemistry.

Basic Information

Product Name	2-Cyclobuten-1-Ol, 1-Ethynyl-4-Methoxy-4-Methyl-, cis- (9Ci)
CAS No.	155190-60-6
Molecular Formula	C8H10O2
Molecular Weight	138.16 g/mol
Synonyms	cis-1-Ethynyl-4-methoxy-4-methyl-2-cyclobuten-1-ol; 1-Ethynyl-4-methoxy-4-methyl-2-cyclobuten-1-ol, cis-; 2-Cyclobuten-1-ol, 1-ethynyl-4-methoxy-4-methyl-, (1R,2S)-rel-; (1R,2S)-rel-1-Ethynyl-4-methoxy-4-methyl-2-cyclobuten-1-ol; 155190-60-6; cis-4-Methoxy-4-methyl-1-ethynyl-2-cyclobuten-1-ol
EINECS	Contact for details

Quality Control

Our production of 2-Cyclobuten-1-Ol, 1-Ethynyl-4-Methoxy-4-Methyl-, cis- (9Ci) adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical characterization, including chiral purity assessment, to ensure consistency and meet the exacting standards required for research and development. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment. We support compliance with relevant research and development guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at controlled room temperature (15-25°C) in a cool, dry, and well-ventilated place. The compound is moisture-sensitive and should be handled under anhydrous conditions to maintain stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% de
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.