Description

tert-Butoxycarbonylamino-Indan-2-Yl-Acetic Acid is a high-purity, protected amino acid derivative used as a critical building block in advanced organic synthesis. This compound is essential for the controlled introduction of the indane-acetic acid pharmacophore into complex molecular architectures. It is primarily utilized by research chemists and process development scientists in the pharmaceutical and biotechnology industries for the synthesis of novel active pharmaceutical ingredients (APIs) and peptide mimetics.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new therapeutic agents, particularly in oncology and central nervous system (CNS) drug discovery.
• Peptidomimetic Synthesis: Serves as a protected amino acid component for constructing non-natural peptide analogs with enhanced metabolic stability and bioavailability.
• Protease Inhibitor Development: Used in the synthesis of potential inhibitors for various enzymes, leveraging the indane scaffold for targeted binding.
• Chemical Biology Research: Employed as a tool compound or building block for labeling studies, probe development, and investigating protein-ligand interactions.
• Process Chemistry & Scale-up: Suitable for use in kilogram-scale laboratory and pilot plant synthesis under current Good Manufacturing Practice (cGMP) guidelines for pre-clinical and clinical trial material production.

Basic Information

Product Name	tert-Butoxycarbonylamino-Indan-2-Yl-Acetic Acid
CAS No.	155172-73-9
Molecular Formula	C₁₆H₂₁NO₄
Molecular Weight	291.34 g/mol
Synonyms	Boc-AIDA-OH; (2-((tert-Butoxycarbonyl)amino)-2,3-dihydro-1H-inden-2-yl)acetic Acid; 2-((tert-Butoxycarbonyl)amino)indane-2-acetic Acid; N-Boc-2-aminoindane-2-acetic Acid; N-(tert-Butoxycarbonyl)-2-aminoindane-2-acetic Acid; tert-Butyl (2-(carboxymethyl)-2,3-dihydro-1H-inden-2-yl)carbamate; 155172-73-9; Boc-Aida-OH
EINECS	Contact for details

Quality Control

Our tert-Butoxycarbonylamino-Indan-2-Yl-Acetic Acid is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide full traceability and Certificates of Analysis (COA) are available for all shipments. Our quality standards are designed to meet the rigorous demands of pharmaceutical R&D and production.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Purity (HPLC, Area %)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.