Description

n-(2,2-Difluoroacetyl)-2,2-Difluoroacetohydrazide is a high-purity, specialized fluorinated organic intermediate of significant interest in advanced chemical synthesis. This compound matters for its role as a key building block in the development of novel pharmaceuticals and agrochemicals, where the introduction of difluoroacetyl groups can dramatically alter biological activity and metabolic stability. It is primarily needed by research and development chemists, process development scientists, and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to incorporate unique fluorinated motifs into their target molecules.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring difluoroacetamide or hydrazide functionalities for enhanced potency and selectivity.
• Agrochemical Synthesis: Used in the research and production of next-generation herbicides, fungicides, and insecticides, where fluorine atoms improve lipophilicity and environmental stability.
• Fluorinated Building Block: Serves as a versatile reagent for introducing the difluoroacetyl group into complex organic molecules during medicinal chemistry and material science research.
• Chemical Research & Development: Employed in academic and industrial labs for exploring new reactions and creating novel fluorinated compounds with potential biological or material properties.
• Ligand and Catalyst Development: Potential use in the design of specialized ligands or organocatalysts for asymmetric synthesis and other catalytic processes.

Basic Information

Item	Details
Product Name	n-(2,2-Difluoroacetyl)-2,2-Difluoroacetohydrazide
CAS No.	155093-22-4
Molecular Formula	C4H4F4N2O2
Molecular Weight	188.08 g/mol
Synonyms	2,2-Difluoro-N'-(2,2-difluoroacetyl)acetohydrazide; 2,2,2',2'-Tetrafluoroacetohydrazide; Difluoroacetic hydrazide, N-(difluoroacetyl)-; N-(2,2-Difluoroacetyl)-2,2-difluoroacetohydrazide; 1-(2,2-Difluoroacetyl)-2-(2,2-difluoroacetyl)hydrazine; Tetrafluoroacetohydrazide
EINECS	Contact for details

Quality Control

Our n-(2,2-Difluoroacetyl)-2,2-Difluoroacetohydrazide is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for assay and purity, and is supplied with a detailed Certificate of Analysis (COA). We are committed to meeting the stringent requirements of cGMP and ISO standards for advanced chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is moisture-sensitive; keep the container tightly sealed under an inert atmosphere if necessary.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (HPLC, Area %)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.