Description

7-[[(1,1-Dimethylethyl)dimethylsilyl]oxy]-1-hepten-3-ol is a high-value organosilicon-protected intermediate, specifically a silyl ether derivative of a hydroxylated alkene. This compound is critical for advanced organic synthesis, offering a protected hydroxyl group that is stable under a wide range of reaction conditions yet can be selectively deprotected. It is primarily sought after by research chemists and process development scientists in the pharmaceutical and fine chemical industries for the synthesis of complex molecules, including active pharmaceutical ingredients (APIs) and novel materials.

Application

• Pharmaceutical Intermediate: Key building block in multi-step synthesis for novel drug candidates and active pharmaceutical ingredients (APIs).
• Asymmetric Synthesis: Used in stereoselective reactions to construct chiral centers due to its functionalized alkene and protected alcohol.
• Polymer & Material Science: Serves as a monomer or functionalizing agent for creating specialty polymers with tailored properties.
• Cross-Coupling Reactions: The alkene and silyl-protected alcohol functionalities make it a suitable substrate for various metal-catalyzed coupling reactions.
• Ligand & Catalyst Development: Utilized in the preparation of novel ligands and organometallic catalysts for research and industrial processes.
• Fine Chemical Production: Intermediate for synthesizing fragrances, flavors, and other high-value specialty chemicals.

Basic Information

Product Name	7-[[(1,1-Dimethylethyl)dimethylsilyl]oxy]-1-hepten-3-ol
CAS No.	154672-42-1
Molecular Formula	C13H28O2Si
Molecular Weight	244.45 g/mol
Synonyms	1-Hepten-3-ol, 7-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-; 7-(tert-Butyldimethylsilyloxy)-1-hepten-3-ol; 7-((tert-Butyldimethylsilyl)oxy)-1-hepten-3-ol; TBDMS-protected 7-hydroxy-1-hepten-3-ol; 3-Hydroxy-1-heptene 7-tert-butyldimethylsilyl ether; tert-Butyldimethyl(7-hydroxy-5-hepten-1-yloxy)silane (tautomeric form); 154672-42-1
EINECS	Contact for details

Quality Control

Our 7-[[(1,1-Dimethylethyl)dimethylsilyl]oxy]-1-hepten-3-ol is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and FTIR, to ensure high purity and consistent identity. Certificates of Analysis (COA) detailing purity, assay, and impurity profiles are provided with each shipment. We support cGMP compliance for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for prolonged storage or after opening to maintain stability and purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC/GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.