Description

Ethyl 4-Acetoxy-6,7-Difluoro-2-(Ethylthio)Quinoline-3-Carboxylate is a high-purity, multi-functional quinoline derivative serving as a critical synthetic intermediate in advanced organic chemistry. This compound matters for its role in constructing complex molecular architectures, particularly in the development of active pharmaceutical ingredients (APIs) and specialty agrochemicals. Pharmaceutical R&D laboratories, agrochemical manufacturers, and fine chemical synthesis specialists need this material for its precise fluorine substitution and reactive ester functionality, which enable targeted modifications in lead optimization and process chemistry.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel fluoroquinolone antibiotics and other drug candidates targeting bacterial infections.
• Agrochemical Synthesis: Precursor for developing advanced crop protection agents, including herbicides and fungicides, leveraging the difluoroquinoline core.
• Material Science Research: Used in the development of organic electronic materials, such as OLED (Organic Light-Emitting Diode) components and charge-transport layers.
• Fluorescent Probe Development: Serves as a scaffold for creating sensitive chemical sensors and bio-imaging agents due to the quinoline fluorophore.
• Organic Synthesis Reagent: Employed in academic and industrial research for constructing complex heterocyclic compounds via its reactive acetoxy and ethylthio groups.
• Chemical Reference Standard: Used as a high-purity analytical standard for quality control and method validation in pharmaceutical and chemical analysis.

Basic Information

Item	Details
Product Name	Ethyl 4-Acetoxy-6,7-Difluoro-2-(Ethylthio)Quinoline-3-Carboxylate
CAS No.	154330-68-4
Molecular Formula	C₁₆H₁₅F₂NO₄S
Molecular Weight	355.36 g/mol
Synonyms	4-Acetoxy-6,7-difluoro-2-(ethylthio)-3-quinolinecarboxylic Acid Ethyl Ester; Ethyl 4-Acetoxy-6,7-difluoro-2-(ethylsulfanyl)quinoline-3-carboxylate; 6,7-Difluoro-2-(ethylthio)-4-hydroxyquinoline-3-carboxylic Acid Ethyl Ester Acetate; 154330-68-4; Quinoline-3-carboxylic acid, 4-(acetyloxy)-6,7-difluoro-2-(ethylthio)-, ethyl ester; Ethyl 4-acetyloxy-6,7-difluoro-2-ethylsulfanylquinoline-3-carboxylate
EINECS	Contact for details

Quality Control

Our Ethyl 4-Acetoxy-6,7-Difluoro-2-(Ethylthio)Quinoline-3-Carboxylate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure compliance with exacting industry standards. Certificates of Analysis (COA) detailing all specifications are available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, open flames, and incompatible materials. Due to its light-sensitive nature, handling should be performed under appropriate conditions to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.