Description

Ethyl 6,7-Difluoro-2-Ethylmercapto-4-Hydroxyquinoline-3-Carboxylate is a high-purity, advanced pharmaceutical intermediate characterized by its complex quinoline-based structure. This compound is critical for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in the development of antibacterial and anti-infective agents. It is primarily utilized by research institutions and manufacturers in the pharmaceutical and fine chemical sectors seeking reliable, high-quality building blocks for complex organic synthesis.

Application

• Key Intermediate for Antibacterial Agents: Serves as a crucial precursor in the synthesis of next-generation fluoroquinolone antibiotics and other antimicrobial compounds.
• Pharmaceutical Research & Development: Used in medicinal chemistry for the discovery and optimization of new drug candidates targeting bacterial infections.
• Fine Chemical Synthesis: Employed as a specialized building block for constructing complex heterocyclic molecules in advanced organic synthesis.
• Active Pharmaceutical Ingredient (API) Manufacturing: Integrated into the production process of final drug substances under controlled GMP environments.
• Contract Research & Manufacturing (CRAM): Supplied to CDMOs for custom synthesis projects requiring high-purity, structurally complex intermediates.

Basic Information

Product Name	Ethyl 6,7-Difluoro-2-Ethylmercapto-4-Hydroxyquinoline-3-Carboxylate
CAS No.	154330-67-3
Molecular Formula	C₁₄H₁₃F₂NO₃S
Molecular Weight	313.32 g/mol
Synonyms	6,7-Difluoro-2-(ethylthio)-4-hydroxyquinoline-3-carboxylic acid ethyl ester; Ethyl 6,7-difluoro-2-(ethylthio)-4-oxo-1,4-dihydroquinoline-3-carboxylate; 2-Ethylmercapto-6,7-difluoro-4-hydroxyquinoline-3-carboxylic acid ethyl ester; 154330-67-3; 6,7-Difluoro-2-ethylsulfanyl-4-hydroxyquinoline-3-carboxylic acid ethyl ester; Ethyl 2-(ethylthio)-6,7-difluoro-4-hydroxyquinoline-3-carboxylate; Quinoline-3-carboxylic acid, 6,7-difluoro-2-(ethylthio)-4-hydroxy-, ethyl ester
EINECS	Contact for details

Quality Control

Our Ethyl 6,7-Difluoro-2-Ethylmercapto-4-Hydroxyquinoline-3-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the stringent requirements for pharmaceutical intermediate applications. Certificates of Analysis (COA) detailing all specifications are available upon request, supporting your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials. The product is light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.